Evidence map›Paper›PMID 28243356›Full record

ArticleOxidative medicine and cellular longevity2017

Evaluation of Anti-Inflammatory Properties of Isoorientin Isolated from Tubers of

Kotha Anilkumar, Gorla V Reddy, Rajaram Azad, Nagendra Sastry Yarla, Gangappa Dharmapuri, Anand Srivastava, Mohammad A Kamal, Reddanna Pallu

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Natural flavonoid isoorientin and its anticancer mechanisms: a systematic review.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Isoorientin Improves Excisional Skin Wound Healing in Mice.Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  9. Antibiotics (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Article
  12. In Silico Studies of Four Compounds ofMolecules (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Anti-Inflammatory Effects of Phytochemical Components ofMolecules (Basel, Switzerland) · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Kotha AnilkumarSchool of Life Sciences, University of Hyderabad, Hyderabad 500046, India; National Institute of Animal Biotechnology, Hyderabad 500049, India.
Gorla V ReddySchool of Life Sciences, University of Hyderabad, Hyderabad 500046, India.
Rajaram AzadSchool of Life Sciences, University of Hyderabad, Hyderabad 500046, India.
Nagendra Sastry YarlaDepartment of Biochemistry and Bioinformatics, School of Life Sciences, Institute of Science, GITAM University, Visakhapatnam, Andhra Pradesh 530 045, India.
Gangappa DharmapuriSchool of Life Sciences, University of Hyderabad, Hyderabad 500046, India.
Anand SrivastavaNational Institute of Animal Biotechnology, Hyderabad 500049, India.
Mohammad A KamalKing Fahd Medical Research Center, King Abdulaziz University, P.O. Box 80216, Jeddah 21589, Saudi Arabia; Enzymoics, 7 Peterlee Place, Hebersham, NSW 2770, Australia; Novel Global Community Educational Foundation, Hebersham, NSW, Australia.ORCID 0000-0003-0088-0565
Reddanna PalluSchool of Life Sciences, University of Hyderabad, Hyderabad 500046, India.ORCID 0000-0001-6343-6758
University of Hyderabad · INGITAM University · INKing Abdulaziz University · SANational Institute of Animal Biotechnology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is the major causative factor of different diseases such as cardiovascular disease, diabetes, obesity, osteoporosis, rheumatoid arthritis, inflammatory bowel disease, and cancer. Anti-inflammatory drugs are often the first step of treatment in many of these diseases. The present study is aimed at evaluating the anti-inflammatory properties of isoorientin, a selective cyclooxygenase-2 (COX-2) inhibitor isolated from the tubers of

Indexed as

AnimalsAnti-Inflammatory AgentsCarrageenanCell SurvivalCytokinesEdemaInflammationInflammation MediatorsLipopolysaccharidesLuteolinMacrophagesMaleMiceMice, Inbred BALB CNF-kappa BPlant ExtractsAnti-Inflammatory AgentsCarrageenanCytokineshomoorientinInflammation MediatorsLipopolysaccharidesLuteolinNF-kappa BPlant Extracts

Identifiers

PMID28243356
PMCPMC5294751
OpenAlexW2580853226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.