Evidence map›Paper›PMID 28243352›Full record

ArticleJournal of vascular and interventional neurology2017

Safety and Efficacy of Intensified Antiplatelet Therapy in Patients Undergoing Neuroendovascular Procedures.

Senka Runjaic, Jerah D Nordeen, Matthew W Soto-Arenall, Gretchen S Johns, David Miller, Benjamin Brown, William D Freeman

Open access · greenAbstract read
In one paragraph

Article in Journal of vascular and interventional neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Senka RunjaicDepartment of Pharmacy, Mayo Clinic, Jacksonville, FL, USA.
Jerah D NordeenDepartment of Pharmacy, Mayo Clinic, Jacksonville, FL, USA.
Matthew W Soto-ArenallDepartment of Pharmacy, Mayo Clinic, Jacksonville, FL, USA.
Gretchen S JohnsDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, FL, USA.
David MillerNeuroendovascular Division, Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, USA.
Benjamin BrownNeuroendovascular Division, Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, USA.
William D FreemanDepartments of Neurology, Neurosurgery, and Critical Care, Mayo Clinic, Jacksonville, FL, USA.
Mayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe purpose of this study was to evaluate safety and efficacy of intensified antiplatelet therapy guided by VerifyNow assay P2Y

methodsAn observational, retrospective review was conducted at a single academic tertiary referral center and comprehensive stroke center from December 1, 2012, to August 31, 2014. The primary objective was to determine the prevalence of thromboembolic complications stratified by preprocedural PRU values. Secondary outcomes were assessed by investigating whether the goal PRU value of 190 or less is sufficient to reduce thromboembolic complications on the day of the procedure, and 30- and 90-day postprocedure.

resultsThere was no statistically significant difference in the overall rate of complications in the two groups (two events in the group with preprocedural PRU values of 190 or more versus seven events in the group with preprocedural PRU values of less than 190,

conclusionThe observed rate of thromboembolic and hemorrhagic complications in patients with preprocedural PRU values of less than 190 was not significantly different from the rate observed in patients with preprocedural PRU values of greater than 190. Sources of funding: No external funding used.

Identifiers

PMID28243352
PMCPMC5317284
OpenAlexW2611690947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.