Evidence map›Paper›PMID 28243294›Full record

ArticleIranian journal of pharmaceutical research : IJPR2016

Randomized Trial of the Effect of Magnesium Sulfate Continuous Infusion on IL-6 and CRP Serum Levels Following Abdominal Aortic Aneurysm Surgery.

Mojtaba Mojtahedzadeh, Legese Chelkeba, Mona Ranjvar-Shahrivar, Atabak Najafi, Majid Moini, Farhad Najmeddin, Kourosh Sadeghi, Khosro Barkhordari, Azin Gheymati, Arezoo Ahmadi

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04894864 (Effect of a Perioperative Opioid Free Anesthesia-Analgesia), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04894864 phase4recruitingnot on this mapstarted 2020, after this paper: background citation

Effect of a Perioperative Opioid Free Anesthesia-Analgesia (OFA-A) Strategy on Surgical Stress Response in Elective Open Abdominal Aortic Aneurysm Repair: A Prospective Randomized Study

TypeinterventionalSponsorUniversity of CreteRan2020 to 2027Enrolled40ConditionsElective Surgical Procedures, Postoperative Pain, Anesthesia, Opioid UseArmsOpioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mojtaba MojtahedzadehDepartment of Anesthesiology and Critical Care, Sina hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. ; Department of Clinical Pharmacy and Pharmaceutical Science Research Center, Tehran University of Medical Sciences, Tehran, Iran.; Faculty of pharmacy and Pharmaceutical Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Legese ChelkebaDepartment of Clinical Pharmacy and Pharmaceutical Science Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mona Ranjvar-ShahrivarFaculty of pharmacy and Pharmaceutical Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Atabak NajafiDepartment of Anesthesiology and Critical Care, Sina hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Majid MoiniDepartment of Surgery, Sina hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Farhad NajmeddinDepartment of Clinical Pharmacy and Pharmaceutical Science Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Kourosh SadeghiDepartment of Clinical Pharmacy and Pharmaceutical Science Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Khosro BarkhordariDepartment of Anesthesiology and Critical Care, Tehran Heart Center, Faculty of Medicine, Tehran University.
Azin GheymatiFaculty of pharmacy and Pharmaceutical Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Arezoo AhmadiDepartment of Anesthesiology and Critical Care, Sina hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal aortic aneurysm (AAA) is widely considered as the disease of elderly white men. Inflammation is one of the most well-known mechanisms involved in the pathogenesis of AAA. Magnesium is one of the most important minerals in the body with established anti-inflammatory effects. In this study, we aimed to investigate the impact of Mg loading following AAA surgery on two inflammation markers, IL-6 and CRP, as well as patient's outcome. This study was conducted as a randomized clinical trial on 18 patients (divided into two groups) after surgical correction of Acute Aortic Aneurysm (AAA). All the patients admitted in ICU ward of Sina Hospital. In intervention group, 10 g of MgSO

Indexed as

Abdominal aortic aneurysm (AAA)C- reactive protein (CRP)Interleukin 6 (IL-6)Magnesium Sulfate (MgSo4)

Identifiers

PMID28243294
PMCPMC5316276
OpenAlexW2571095082

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.