Evidence map›Paper›PMID 28243252›Full record

ReviewGastroenterology research and practice2017

Neurobiological Mechanism of Acupuncture for Relieving Visceral Pain of Gastrointestinal Origin.

Fang Zhang, Luyi Wu, Jimeng Zhao, Tingting Lv, Zhihai Hu, Zhijun Weng, Shuoshuo Wang, Huangan Wu, Huirong Liu

Open access · goldAbstract readReview
In one paragraph

Review in Gastroenterology research and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. P2X7 and P2YPurinergic signalling · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. P2XGastroenterology research and practice · 2020
    Article
  15. Review
  16. Central and Peripheral Mechanism of Acupuncture Analgesia on Visceral Pain: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2019
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fang ZhangShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China.ORCID 0000-0002-3506-8924
Luyi WuShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China.ORCID 0000-0001-8888-1698
Jimeng ZhaoShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China.
Tingting LvShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China.ORCID 0000-0001-5529-1851
Zhihai HuShanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China.ORCID 0000-0001-6662-1596
Zhijun WengShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China.ORCID 0000-0001-9402-3657
Shuoshuo WangShanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China.ORCID 0000-0002-4005-9280
Huangan WuShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China.ORCID 0000-0003-1725-6881
Huirong LiuShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China.ORCID 0000-0002-5132-1141
Shanghai Research Center for Acupuncture and Meridians · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is currently accepted that the neural transduction pathways of gastrointestinal (GI) visceral pain include the peripheral and central pathways. Existing research on the neurological mechanism of electroacupuncture (EA) in the treatment of GI visceral pain has primarily been concerned with the regulation of relevant transduction pathways. The generation of pain involves a series of processes, including energy transduction of stimulatory signals in the sensory nerve endings (signal transduction), subsequent conduction in primary afferent nerve fibers of dorsal root ganglia, and transmission to spinal dorsal horn neurons, the ascending transmission of sensory signals in the central nervous system, and the processing of sensory signals in the cerebral cortex. Numerous peripheral neurotransmitters, neuropeptides, and cytokines participate in the analgesic process of EA in visceral pain. Although EA has excellent efficacy in the treatment of GI visceral pain, the pathogenesis of the disease and the analgesic mechanism of the treatment have not been elucidated. In recent years, research has examined the pathogenesis of GI visceral pain and its influencing factors and has explored the neural transduction pathways of this disease.

Identifiers

PMID28243252
PMCPMC5294365
OpenAlexW2582993933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.