Evidence map›Paper›PMID 28243233›Full record

ArticleFrontiers in immunology2017

Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes.

Pablo García-Valtanen, Alicia Martínez-López, Azucena López-Muñoz, Melissa Bello-Perez, Regla M Medina-Gali, María Del Mar Ortega-Villaizán, Monica Varela, Antonio Figueras, Víctoriano Mulero, Beatriz Novoa and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
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  6. Inflammation in Development and Aging: Insights from the Zebrafish Model.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Review
  9. Article
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  11. Article
  12. ZebrafishVaccines · 2020
    Article
  13. Article
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  15. Article
  16. Evidence of Trained Immunity in a Fish: Conserved Features in Carp Macrophages.Journal of immunology (Baltimore, Md. : 1950) · 2019
    Article
  17. Article
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  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Pablo García-ValtanenDepartamento de Bioquímica, Universidad Miguel Hernández de Elche (UMH) , Alicante , Spain.
Alicia Martínez-LópezDepartamento de Bioquímica, Universidad Miguel Hernández de Elche (UMH) , Alicante , Spain.
Azucena López-MuñozFacultad de Biología, Departamento de Biología Celular e Histología, Universidad de Murcia, IMIB-Arrixaca , Murcia , Spain.
Melissa Bello-PerezDepartamento de Bioquímica, Universidad Miguel Hernández de Elche (UMH) , Alicante , Spain.
Regla M Medina-GaliDepartamento de Bioquímica, Universidad Miguel Hernández de Elche (UMH) , Alicante , Spain.
María Del Mar Ortega-VillaizánDepartamento de Bioquímica, Universidad Miguel Hernández de Elche (UMH) , Alicante , Spain.
Monica VarelaInstituto de Investigaciones Marinas (IIM), Consejo Superior de Investigaciones Científicas (CSIC) , Vigo , Spain.
Antonio FiguerasInstituto de Investigaciones Marinas (IIM), Consejo Superior de Investigaciones Científicas (CSIC) , Vigo , Spain.
Víctoriano MuleroFacultad de Biología, Departamento de Biología Celular e Histología, Universidad de Murcia, IMIB-Arrixaca , Murcia , Spain.
Beatriz NovoaInstituto de Investigaciones Marinas (IIM), Consejo Superior de Investigaciones Científicas (CSIC) , Vigo , Spain.
Amparo EstepaDepartamento de Bioquímica, Universidad Miguel Hernández de Elche (UMH) , Alicante , Spain.
Julio CollDepartamento de Biotecnología, Instituto Nacional Investigación y Tecnología Agraria y Alimentaria (INIA) , Madrid , Spain.
Universitat de Miguel Hernández d'Elx · ESInstituto de Investigacións Mariñas · ESUniversidad de Murcia · ESConsejo Superior de Investigaciones Científicas · ESInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate fish innate immunity, we have conducted organ and cell immune-related transcriptomic as well as immunohistologic analysis in mutant zebra fish (

Indexed as

antiviral alert statemultigene families and apoptosis in resistance to viral infectionsspring viremia carp viral infectionstrained immunity NK/macrophages in fishzebra fish rag1−/− adaptive deficient mutants

Identifiers

PMID28243233
PMCPMC5303895
OpenAlexW2588256588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.