Evidence map›Paper›PMID 28243230›Full record

ArticleFrontiers in microbiology2017

First Report of CD4 Lymphopenia and Defective Neutrophil Functions in a Patient with Amebiasis Associated with CMV Reactivation and Severe Bacterial and Fungal Infections.

Etienne Ghrenassia, Amélie Guihot, Yuan Dong, Pauline Robinet, Thierry Fontaine, Karine Lacombe, Thomas Lescot, Marie-Caroline Meyohas, Carole Elbim

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Effects ofPeerJ · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Etienne GhrenassiaAP-HP, Hôpital Saint-Antoine, Service des Maladies Infectieuses et Tropicales Paris, France.
Amélie GuihotDépartement d'Immunologie, AP-HP, Hôpital Pitié-SalpêtrièreParis, France; DHU FAST, CR7, Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Universités, UPMC Univ Paris 06Paris, France; Institut National de la Santé et de la Recherche Médicale, U1135, Centre d'Immunologie et des Maladies Infectieuses-ParisParis, France.
Yuan DongInstitut National de la Santé et de la Recherche Médicale, Centre de Recherche Saint-Antoine, UMR-S 938 Paris, France.
Pauline RobinetDHU FAST, CR7, Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Universités, UPMC Univ Paris 06Paris, France; Institut National de la Santé et de la Recherche Médicale, U1135, Centre d'Immunologie et des Maladies Infectieuses-ParisParis, France.
Thierry FontaineInstitut Pasteur, Unité des Aspergillus Paris, France.
Karine LacombeAP-HP, Hôpital Saint-Antoine, Service des Maladies Infectieuses et Tropicales Paris, France.
Thomas LescotUnité de Réanimation Chirurgicale Digestive, Département D'anesthésie et de Réanimation Chirurgicale, AP-HP, Hôpital Saint-Antoine Paris, France.
Marie-Caroline MeyohasAP-HP, Hôpital Saint-Antoine, Service des Maladies Infectieuses et Tropicales Paris, France.
Carole ElbimDHU FAST, CR7, Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Universités, UPMC Univ Paris 06Paris, France; Institut National de la Santé et de la Recherche Médicale, U1135, Centre d'Immunologie et des Maladies Infectieuses-ParisParis, France.
Sorbonne Université · FRAssistance Publique – Hôpitaux de Paris · FRCentre d'Immunologie et des Maladies Infectieuses · FRCentre de Recherche Saint-Antoine · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a patient with acute necrotizing colitis due to invasive amebiasis associated with CD4 lymphopenia and impaired neutrophil responses. The course of the disease was characterized by CMV reactivation and severe and recurrent bacterial and fungal infections, which might be related to the decreased CD4 T cell count and the impaired functional capacities of neutrophils, respectively. The clinical outcome was positive with normalization of both CD4 cell count and neutrophil functions.

Indexed as

amebiasisaspergillosisCD4 T cellscytomegalovirusneutrophils

Identifiers

PMID28243230
PMCPMC5303735
OpenAlexW2586084066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.