Evidence map›Paper›PMID 28243212›Full record

ArticleFrontiers in psychiatry2017

Transient Dysregulation of Dopamine Signaling in a Developing

Lachlan Ferguson, Alice Petty, Chelsie Rohrscheib, Michael Troup, Leonie Kirszenblat, Darryl W Eyles, Bruno van Swinderen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Beyond vertebrates:Frontiers in psychiatry · 2025
    Review
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  7. Activity-Dependent Global Downscaling of Evoked Neurotransmitter Release across Glutamatergic Inputs inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Sleep regulates visual selective attention inThe Journal of experimental biology · 2018
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lachlan FergusonQueensland Brain Institute, The University of Queensland , Brisbane, QLD , Australia.
Alice PettyQueensland Brain Institute, The University of Queensland , Brisbane, QLD , Australia.
Chelsie RohrscheibQueensland Brain Institute, The University of Queensland , Brisbane, QLD , Australia.
Michael TroupQueensland Brain Institute, The University of Queensland , Brisbane, QLD , Australia.
Leonie KirszenblatQueensland Brain Institute, The University of Queensland , Brisbane, QLD , Australia.
Darryl W EylesQueensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia; Queensland Centre for Mental Health Research, Wacol, QLD, Australia.
Bruno van SwinderenQueensland Brain Institute, The University of Queensland , Brisbane, QLD , Australia.
University of Queensland · AU

Funding

Functional Analysis of Sleep Promoting Neurons in Health and DiseaseR01NS076980 · NINDS · WASHINGTON UNIVERSITY · PI SHAW, PAUL J · 2011 to 2020
$3.3M
NINDS NIH HHS R01 NS076980
6 · The paper itself

Abstract

The dopamine ontogeny hypothesis for schizophrenia proposes that transient dysregulation of the dopaminergic system during brain development increases the likelihood of this disorder in adulthood. To test this hypothesis in a high-throughput animal model, we have transiently manipulated dopamine signaling in the developing fruit fly

Indexed as

D1 receptorgeneticsontogenyschizophreniasleepvisual

Identifiers

PMID28243212
PMCPMC5304146
OpenAlexW2587878891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.