Evidence map›Paper›PMID 28243198›Full record

ReviewFrontiers in aging neuroscience2017

Non-Invasive Brain Stimulation: A New Strategy in Mild Cognitive Impairment?

Agustina Birba, Agustín Ibáñez, Lucas Sedeño, Jesica Ferrari, Adolfo M García, Máximo Zimerman

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 5 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 5 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 4 countries.

Agustina BirbaLaboratory of Experimental Psychology and Neuroscience (LPEN), Institute of Cognitive and Translational Neuroscience (INCyT), INECO Foundation, Favaloro UniversityBuenos Aires, Argentina; National Scientific and Technical Research Council (CONICET)Buenos Aires, Argentina.
Agustín IbáñezLaboratory of Experimental Psychology and Neuroscience (LPEN), Institute of Cognitive and Translational Neuroscience (INCyT), INECO Foundation, Favaloro UniversityBuenos Aires, Argentina; National Scientific and Technical Research Council (CONICET)Buenos Aires, Argentina; Universidad Autónoma del CaribeBarranquilla, Colombia; Center for Social and Cognitive Neuroscience (CSCN), School of Psychology, Universidad Adolfo IbañezSantiago de Chile, Chile; Centre of Excellence in Cognition and its Disorders, Australian Research Council (ARC)Sydney, NSW, Australia.
Lucas SedeñoLaboratory of Experimental Psychology and Neuroscience (LPEN), Institute of Cognitive and Translational Neuroscience (INCyT), INECO Foundation, Favaloro UniversityBuenos Aires, Argentina; National Scientific and Technical Research Council (CONICET)Buenos Aires, Argentina.
Jesica FerrariLaboratory of Experimental Psychology and Neuroscience (LPEN), Institute of Cognitive and Translational Neuroscience (INCyT), INECO Foundation, Favaloro University Buenos Aires, Argentina.
Adolfo M GarcíaLaboratory of Experimental Psychology and Neuroscience (LPEN), Institute of Cognitive and Translational Neuroscience (INCyT), INECO Foundation, Favaloro UniversityBuenos Aires, Argentina; National Scientific and Technical Research Council (CONICET)Buenos Aires, Argentina; Faculty of Education, National University of Cuyo (UNCuyo)Mendoza, Argentina.
Máximo ZimermanLaboratory of Experimental Psychology and Neuroscience (LPEN), Institute of Cognitive and Translational Neuroscience (INCyT), INECO Foundation, Favaloro University Buenos Aires, Argentina.
Instituto de Neurología Cognitiva · ARCentro Científico Tecnológico - San Juan · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-invasive brain stimulation (NIBS) techniques can significantly modulate cognitive functions in healthy subjects and patients with neuropsychiatric disorders. Recently, they have been applied in patients with mild cognitive impairment (MCI) and subjective cognitive impairment (SCI) to prevent or delay the development of Alzheimer's disease (AD). Here we review this emerging empirical corpus and discuss therapeutic effects of NIBS on several target functions (e.g., memory for face-name associations and non-verbal recognition, attention, psychomotor speed, everyday memory). Available studies have yielded mixed results, possibly due to differences among their tasks, designs, and samples, let alone the latter's small sizes. Thus, the impact of NIBS on cognitive performance in MCI and SCI remains to be determined. To foster progress in this direction, we outline methodological approaches that could improve the efficacy and specificity of NIBS in both conditions. Furthermore, we discuss the need for multicenter studies, accurate diagnosis, and longitudinal approaches combining NIBS with specific training regimes. These tenets could cement biomedical developments supporting new treatments for MCI and preventive therapies for AD.

Indexed as

mild cognitive impairmentneuroenhancementnon-invasive brain stimulationtranscranial direct current stimulationtranscranial magnetic stimulation

Identifiers

PMID28243198
PMCPMC5303733
OpenAlexW2587000139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.