Evidence map›Paper›PMID 28243086›Full record

ReviewInternational journal of nanomedicine2017

The antimicrobial activity of nanoparticles: present situation and prospects for the future.

Linlin Wang, Chen Hu, Longquan Shao

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,060 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,060citing papers in PubMed, 2 pooled it
104.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,060 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3,843 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Review
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  8. Multifactorial Role of Phytogenic CeOPlant-environment interactions (Hoboken, N.J.) · 2026
    Review
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  16. Green-synthesized metal oxide nanoparticles enhance the antibacterial activity of Portulaca oleracea through foliar nano-elicitation.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
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  19. Review
  20. Article

1,000 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Linlin WangDepartment of Stomatology, Hainan General Hospital, Haikou, Hainan.
Chen HuDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Longquan ShaoDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Hainan General Hospital · CNNanfang Hospital · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles (NPs) are increasingly used to target bacteria as an alternative to antibiotics. Nanotechnology may be particularly advantageous in treating bacterial infections. Examples include the utilization of NPs in antibacterial coatings for implantable devices and medicinal materials to prevent infection and promote wound healing, in antibiotic delivery systems to treat disease, in bacterial detection systems to generate microbial diagnostics, and in antibacterial vaccines to control bacterial infections. The antibacterial mechanisms of NPs are poorly understood, but the currently accepted mechanisms include oxidative stress induction, metal ion release, and non-oxidative mechanisms. The multiple simultaneous mechanisms of action against microbes would require multiple simultaneous gene mutations in the same bacterial cell for antibacterial resistance to develop; therefore, it is difficult for bacterial cells to become resistant to NPs. In this review, we discuss the antibacterial mechanisms of NPs against bacteria and the factors that are involved. The limitations of current research are also discussed.

Indexed as

AnimalsAnti-Infective AgentsBacteriaDrug Resistance, BacterialHumansMetal NanoparticlesNanotechnologyAnti-Infective Agentsantimicrobial activityantimicrobial resistancenanoparticlesoxidative stress

Identifiers

PMID28243086
PMCPMC5317269
OpenAlexW2589067428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.