Evidence map›Paper›PMID 28243083›Full record

ArticleInternational journal of nanomedicine2017

Heterogeneous dimer peptide-conjugated polylysine dendrimer-Fe

Jian-Min Shen, Xin-Xin Li, Lin-Lan Fan, Xing Zhou, Ji-Min Han, Ming-Kang Jia, Liang-Fan Wu, Xiao-Xue Zhang, Jing Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jian-Min ShenSchool of Life Sciences.
Xin-Xin LiSchool of Life Sciences.
Lin-Lan FanSchool of Basic Medical Sciences, Lanzhou University.
Xing ZhouThe People's Hospital of Gansu Province, Lanzhou, Gansu, China.
Ji-Min HanSchool of Life Sciences.
Ming-Kang JiaSchool of Life Sciences.
Liang-Fan WuSchool of Life Sciences.
Xiao-Xue ZhangSchool of Life Sciences.
Jing ChenSchool of Life Sciences.
Gansu Provincial Hospital · CNLanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel nanoscale molecular probe is formulated in order to reduce toxicity and side effects of antitumor drug doxorubicin (DOX) in normal tissues and to enhance the detection sensitivity during early imaging diagnosis. The mechanism involves a specific targeting of Arg-Gly-Asp peptide (RGD)-GX1 heterogeneous dimer peptide-conjugated dendrigraft poly-l-lysine (DGL)-magnetic nanoparticle (MNP) composite by α

Indexed as

Early DiagnosisAnimalsAntineoplastic AgentsApoptosisCarcinoma, HepatocellularCaspase 3Cell Line, TumorCell SurvivalDendrimersDoxorubicinDrug Liberationfas ReceptorFlow CytometryHep G2 CellsHumansLiver NeoplasmsAntineoplastic AgentsCaspase 3DendrimersDoxorubicinFAS protein, humanfas ReceptorMagnetite NanoparticlesMolecular ProbesPeptidesPolylysinehepatocellular carcinoma (HCC)heterogeneous dimer peptide (HDP)magnetic nanoparticles (MNPs)molecular probetargeting

Identifiers

PMID28243083
PMCPMC5315215
OpenAlexW2586409933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.