ArticleInternational journal of chronic obstructive pulmonary disease2017
MiR-344b-1-3p targets TLR2 and negatively regulates TLR2 signaling pathway.
Article in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Exploring the Roles of Wnt Signaling Pathway and Non-Coding RNAs in COPD.International journal of chronic obstructive pulmonary disease · 2026Review
- MicroRNAs as promising drug delivery target to ameliorate chronic obstructive pulmonary disease using nano-carriers: a comprehensive review.Molecular and cellular biochemistry · 2025Review
- Orchestrating inflammation: non-coding RNAs as master regulators of macrophage function in chronic obstructive pulmonary disease-an update.Frontiers in immunology · 2025Review
- Identification of differentially expressed genes and SNPs linked to harvest body weight of genetically improved rohu carp,Frontiers in genetics · 2023Article
- MicroRNA Control Lipid-laden Alveolar Macrophages in Smokers: A Potential Therapeutic Target for Chronic Obstructive Pulmonary Disease?American journal of respiratory cell and molecular biology · 2022Article
- The miRNA: a small but powerful RNA for COVID-19.Briefings in bioinformatics · 2021Review
- miR-26a-5p mediates TLR signaling pathway by targeting CTGF in LPS-induced alveolar macrophage.Bioscience reports · 2020Article
- MicroRNAs as Potential Regulators of Immune Response Networks in Asthma and Chronic Obstructive Pulmonary Disease.Frontiers in immunology · 2020Review
- Identification of candidate genes and miRNAs associated with neuropathic pain induced by spared nerve injury.International journal of molecular medicine · 2019Article
- Next-generation sequencing predicts interaction network between miRNA and target genes in lipoteichoic acid-stimulated human neutrophils.International journal of molecular medicine · 2019Article
- miRNA-344b-1-3p modulates the autophagy of NR8383 cells duringExperimental and therapeutic medicine · 2019Article
- microRNA-503 contribute to pancreatic beta cell dysfunction by targeting the mTOR pathway in gestational diabetes mellitus.EXCLI journal · 2017Article
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Authors and funding
8 authors.
Funding
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Abstract
objectivesCOPD is an abnormal inflammatory response characterized by decreased expression of TLR2 in patients, which is suggested to induce invasive pulmonary aspergillosis (IPA). MicroRNAs (miRNAs) have been shown to play important roles in the pathogenesis of human respiratory system disorders. Therefore, the aim of this study was to identify the miRNAs involved in the regulation of TLR2 signaling in COPD. MATERIALS AND
methodsmiRNA microarray analysis was performed to screen for the dysregulated miRNAs in alveolar macrophages (AMs) isolated from COPD rats. The interaction between these miRNAs and
resultsCOPD rat model was successfully induced by smoke inhalation. Among the 11 upregulated miRNAs in AMs from COPD rats, miR-344b-1-3p was predicted to be a novel miRNA targeting
conclusionFindings outlined in this study suggest that miR-344b-1-3p was an effective modulator of
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