Observational studyInternational journal of chronic obstructive pulmonary disease2017
Longitudinal changes in structural abnormalities using MDCT in COPD: do the CT measurements of airway wall thickness and small pulmonary vessels change in parallel with emphysematous progression?
Observational study in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Chest CT in the evaluation of chronic obstructive pulmonary disease: recommendations of Asian Society of Thoracic Radiology.The British journal of radiology · 2026Guideline
- Automated 3D Quantitative Analysis of Intrapulmonary Vessel Volume on Noncontrast CT in Healthy Individuals.Current medical imaging · 2025Article
- Article
- Quantitative Assessment Characteristics of Small Pulmonary Vessel Remodelling in Populations at High Risk for COPD and Smokers Using Low-Dose CT.International journal of chronic obstructive pulmonary disease · 2024Article
- The utility of quantitative computed tomography in cohort studies of chronic obstructive pulmonary disease: a narrative review.Journal of thoracic disease · 2023Review
- GOLD stage-specific phenotyping of emphysema and airway disease using quantitative computed tomography.Frontiers in medicine · 2023Article
- Quantitative assessment the longitudinal changes of pulmonary vascular counts in chronic obstructive pulmonary disease.Respiratory research · 2022Article
- Contributions of Emphysema and Functional Small Airway Disease on Intrapulmonary Vascular Volume in COPD.International journal of chronic obstructive pulmonary disease · 2022Article
- Correlations of Computed Tomography Measurement of Distal Pulmonary Vascular Pruning with Airflow Limitation and Emphysema in COPD Patients.International journal of chronic obstructive pulmonary disease · 2022Article
- Re-Defining High Risk COPD with Parameter Response Mapping Based on Machine Learning Models.International journal of chronic obstructive pulmonary disease · 2022Article
- Article
- The CT pulmonary vascular parameters and disease severity in COPD patients on acute exacerbation: a correlation analysis.BMC pulmonary medicine · 2021Article
- Article
- Ursolic acid alleviates airway-vessel remodeling and muscle consumption in cigarette smoke-induced emphysema rats.BMC pulmonary medicine · 2019Article
- Longitudinal changes in structural lung abnormalities using MDCT in chronic obstructive pulmonary disease with asthma-like features.PloS one · 2019Observational
- Article
- Understanding low COPD exacerbation rates in Japan: a review and comparison with other countries.International journal of chronic obstructive pulmonary diseaseReview
- Lung Features in Individuals with Biomass Smoke Exposure Characterized by CT Scan and Changes in Pulmonary Function.International journal of chronic obstructive pulmonary diseaseArticle
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent advances in multidetector computed tomography (MDCT) facilitate acquiring important clinical information for managing patients with COPD. MDCT can detect the loss of lung tissue associated with emphysema as a low-attenuation area (LAA) and the thickness of airways as the wall area percentage (WA%). The percentage of small pulmonary vessels <5 mm
methodsWe performed pulmonary function tests (PFTs), an MDCT, and a COPD assessment test (CAT) in 58 patients with COPD at the time of their enrollment at the hospital and 2 years later. We analyzed the change in clinical parameters including CT indices and examined the effect of exacerbations and smoking cessation on the structural changes.
resultsThe CAT score and forced expiratory volume in 1 second (FEV
conclusionThe WA% at the distal bronchi and the %CSA <5 did not change in parallel with parameters of LAA over the same period. We propose that airway disease and vascular remodeling may be reversible to some extent by smoking cessation and appropriate treatment. Optimal management may have a greater effect on pulmonary vascularity and airway disease than parenchymal deconstruction in the early stage of COPD.
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