Evidence map›Paper›PMID 28243067›Full record

ArticlePatient preference and adherence2017

Insulin adherence and persistence among Chinese patients with type 2 diabetes: a retrospective database analysis.

Xiaoning He, Liming Chen, Ke Wang, Haiya Wu, Jing Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Patient preference and adherence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiaoning HeDepartment of Health Pharmacy and Administration, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin.
Liming ChenDepartment of Metabolic Disease, Tianjin Medical University Metabolic Diseases Hospital, Tianjin.
Ke WangMedical Department, Lilly Suzhou Pharmaceutical Company, Ltd., Shanghai, People's Republic of China.
Haiya WuMedical Department, Lilly Suzhou Pharmaceutical Company, Ltd., Shanghai, People's Republic of China.
Jing WuDepartment of Health Pharmacy and Administration, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin.
Tianjin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess adherence and persistence to insulin therapy and identify its associated factors among Chinese insulin-naïve patients with type 2 diabetes (T2D).

methodsTianjin Urban Employee Basic Medical Insurance claims database was used (2008-2011). Adult patients with T2D who initiated insulin therapy during January 2009 through December 2010 and were continuously enrolled for 12 months pre-(baseline) and 12 months post-initiation (follow-up) were included. Patients who had a ≥80% medication possession ratio were deemed adherent, while patients who had no gaps of ≥90 days in insulin therapy were deemed persistent. Associated factors of insulin adherence and persistence were detected by univariate and multivariate analyses.

resultsA total of 24,192 patients were included; the patients had a mean age of 58.9 years, with 49.5% being female. About 51.9% of the patients had human insulin as initiation therapy, while 39.1% were initiated with insulin analog and 9.0% with animal-derived insulin. Premixed insulin (77.3%) was prescribed most often in comparison with basal (11.8%) and prandial (10.9%) insulin. Only 30.9% of patients were adherent, and the mean (standard deviation) medication possession ratio was 0.499 (0.361). About 53.0% of patients persisted insulin therapy during follow-up, and the mean time to nonpersistence was 230.3 (145.5) days. Patients initiated with analog were more likely to be adherent (adjusted odds ratio: 1.07,

conclusionThe insulin adherence and persistence among Chinese patients with T2D are generally poor. Initiation with insulin analog or premixed insulin may result in better adherence/persistence to insulin therapy.

Indexed as

adherenceinsulinpersistencetype 2 diabetes mellitus

Identifiers

PMID28243067
PMCPMC5315350
OpenAlexW2588192276

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.