Evidence map›Paper›PMID 28242814›Full record

ArticlePhysiological reports2017

Microstimulation of single human motor axons in the toe extensors: force production during long-lasting trains of irregular and regular stimuli.

Michael Leitch, Vaughan G Macefield

Abstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael LeitchSchool of Medicine Western Sydney University, Sydney, Australia m.leitch@uws.edu.au.
Vaughan G MacefieldSchool of Medicine Western Sydney University, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human motoneurones are known to discharge with a physiological variability of ~25% during voluntary contractions. Using microstimulation of single human motor axons, we have previously shown that delivering brief trains (10 pulses) of irregular stimuli, which incorporate discharge variability, generates greater contractile responses than trains of regular stimuli with identical mean frequency but zero variability. We tested the hypothesis that longer irregular (physiological) trains would produce greater contractile responses than regular (nonphysiological) trains of the same mean frequency (18 Hz) and duration (45 sec). Tungsten microelectrodes were inserted into the common peroneal nerve of human subjects, and single motor axons supplying the toe extensors (

Indexed as

AdolescentAdultAxonsElectric StimulationElectromyographyFemaleHumansMaleMotor NeuronsMuscle ContractionMuscle, SkeletalToesYoung AdultDischarge variabilityforce generationmicrostimulationsingle axons

Identifiers

PMID28242814
PMCPMC5328761

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.