Observational studyBMJ open2017
Onset seasons and clinical outcomes in patients with Stanford type A acute aortic dissection: an observational retrospective study.
Observational study in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 15 citations in OpenAlex.
- Patterns in acute aortic dissection and a connection to meteorological conditions in Germany.PloS one · 2024Article
- Seasonal and daily variations in the occurence and outcomes of acute Stanford type A dissections: a retrospective single-center study.Journal of cardiothoracic surgery · 2023Article
- The intervention seasons of thoracic endovascular aortic repair impacted the outcomes for patients with type B aortic dissection.Frontiers in cardiovascular medicine · 2023Article
- Effects of seasonal and climate variations on in-hospital mortality and length of stay in patients with type A aortic dissection.Journal of cardiothoracic surgery · 2021Article
- Impact of meteorological conditions and PM2.5 on the onset of acute aortic dissection in monsoonal climate.Journal of geriatric cardiology : JGC · 2018Article
Corrections and comments
- Erratum issuedCorrection:2018
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the association of onset season with clinical outcome in type A acute aortic dissection (AAD).
designA single-centre, observational retrospective study.
settingThe study was conducted in Fuwai Hospital, the National Centre for Cardiovascular Disease, Beijing, China.
participantsFrom 2008 to 2010, a set of consecutive patients with type A AAD, confirmed by CT scanning, were enrolled and divided into four groups according to onset season: winter (December, January and February), spring (March, April and May), summer (June, July and August) and autumn (September, October and November). The primary end points were in-hospital death and all-cause mortality during follow-up.
resultsOf the 492 cases in this study, 129 occurred in winter (26.2%), 147 in spring (29.9%), 92 in summer (18.7%), and 124 in autumn (25.2%). After a median follow-up of 20.4 months (IQR 9.7-38.9), the in-hospital mortality in cases occurring in autumn was higher than in the other three seasons (23.4% vs 8.4%, p<0.01). Long-term mortality was comparable among the four seasonal groups (p=0.63). After adjustment for age, gender and other risk factors, onset in autumn was still an independent factor associated with increased risk of in-hospital mortality (HR 2.05; 95% CI 1.15 to 3.64, p=0.02) in addition to surgical treatment. Further analysis showed that the seasonal effect on in-hospital mortality (autumn vs other seasons: 57.4% vs 27.3%, p<0.01) was only significant in patients who did not receive surgical treatment. No seasonal effect on long-term clinical outcomes was found in this cohort.
conclusionsOnset in autumn may be a factor that increases the risk of in-hospital death from type A AAD, especially in patients who receive conservative treatment. Immediate surgery improves the short-term and long-term outcomes regardless of onset season.
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