ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2017
Inhibitory dysfunction contributes to some of the motor and non-motor symptoms of movement disorders and psychiatric disorders.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 63 citations in OpenAlex.
- Trial
- Neuroinflammation and noradrenergic modulation with β2-adrenoceptors: Emerging therapeutic targets for Parkinson's diseases.Neural regeneration research · 2026Article
- Altered Saccades, Blink and Pupil Responses in Functional Motor Disorder: New Insight Into Neurobiological Mechanisms.European journal of neurology · 2026Article
- Hyperdirect projections from the supplementary motor area mediate subthalamic stimulation effects on movement initiation and inhibition in Parkinson's disease.Brain communications · 2026Article
- Memory in Psychiatric Disorders: A Review.Life (Basel, Switzerland) · 2025Review
- Measuring the nonselective effects of motor inhibition using isometric force recordings.Behavior research methods · 2024Article
- Implication of regional selectivity of dopamine deficits in impaired suppressing of involuntary movements in Parkinson's disease.Neuroscience and biobehavioral reviews · 2024Review
- Antipsychotics and chronic dystonia at a Botulinum Toxin clinic.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024Article
- Increased Frequency of Self-Reported Obsessive-Compulsive Symptoms in Patients with Functional Movement Disorders.Movement disorders clinical practice · 2023Article
- From anticipation to impulsivity in Parkinson's disease.NPJ Parkinson's disease · 2022Article
- Tics: neurological disorders determined by a deficit in sensorimotor gating processes.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Review
- Proactive inhibition is marked by differences in the pattern of motor cortex activity during movement preparation and execution.Journal of neurophysiology · 2022Article
- Neural Correlates of Executive Functioning in Anorexia Nervosa and Obsessive-Compulsive Disorder.Frontiers in human neuroscience · 2022Review
- Towards real-world generalizability of a circuit for action-stopping.Nature reviews. Neuroscience · 2021Review
- Proactive inhibition is not modified by deep brain stimulation for Parkinson's disease: An electrical neuroimaging study.Human brain mapping · 2021Article
- The Human Basal Ganglia Mediate the Interplay between Reactive and Proactive Control of Response through Both Motor Inhibition and Sensory Modulation.Brain sciences · 2021Article
- Inhibitory Control on a Stop Signal Task in Tourette Syndrome before and after Deep Brain Stimulation of the Internal Segment of the Globus Pallidus.Brain sciences · 2021Article
- Impaired Spatial Inhibition Processes for Interhemispheric Anti-saccades following Dorsal Posterior Parietal Lesions.Cerebral cortex communications · 2021Article
- GABAergic Modulation in Movement Related Oscillatory Activity: A Review of the Effect Pharmacologically and with Aging.Tremor and other hyperkinetic movements (New York, N.Y.) · 2021Review
- Temporally-precise disruption of prefrontal cortex informed by the timing of beta bursts impairs human action-stopping.NeuroImage · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, it has been proposed that similar to goal-directed and habitual action mediated by the fronto-striatal circuits, the fronto-striato-subthalamic-pallidal-thalamo-cortical network may also mediate goal-directed and habitual (automatic) inhibition in both the motor and non-motor domains. Within this framework, some of the clinical manifestations of Parkinson's disease, dystonia, Tourette syndrome and obsessive-compulsive disorder can be considered to represent an imbalance between goal-directed and habitual action and inhibition. It is possible that surgical interventions targeting the basal ganglia nuclei, such as deep brain stimulation of the subthalamic nucleus or the internal segment of the globus pallidus, improve these disorders by restoring a functional balance between facilitation and inhibition in the fronto-striatal networks. These proposals require investigation in future studies.This article is part of the themed issue 'Movement suppression: brain mechanisms for stopping and stillness'.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.