Evidence map›Paper›PMID 28242673›Full record

ArticleAntimicrobial agents and chemotherapy2017

The Bifunctional Enzyme SpoT Is Involved in the Clarithromycin Tolerance of Helicobacter pylori by Upregulating the Transporters HP0939, HP1017, HP0497, and HP0471.

Xiwen Geng, Wen Li, Zhenghong Chen, Sizhe Gao, Wei Hong, Xiaoran Ge, Guihua Hou, Zhekai Hu, Yabin Zhou, Beini Zeng and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. International journal of molecular sciences · 2024
    Review
  3. Article
  4. SpoT-mediated NapA upregulation promotes oxidative stress-inducedAntimicrobial agents and chemotherapy · 2023
    Article
  5. Article
  6. Review
  7. Biofilm Formation ofFrontiers in cellular and infection microbiology · 2022
    Article
  8. Article
  9. Review
  10. Trends inMicrobial genomics · 2020
    Review
  11. Analysis of culturable microbiota present in the stomach of children with gastric symptoms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2019
    Article
  12. A Newly Discovered Drug Resistance GeneInfection and drug resistance · 2019
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Xiwen GengDepartment of Microbiology, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Wen LiDepartment of Microbiology, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Zhenghong ChenDepartment of Microbiology, Guiyang Medical University, Guiyang, Guizhou, People's Republic of China.
Sizhe GaoDepartment of Microbiology, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Wei HongDepartment of Microbiology, Guiyang Medical University, Guiyang, Guizhou, People's Republic of China.
Xiaoran GeDepartment of Microbiology, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Guihua HouLaboratory of Experimental Teratology, Ministry of Education and Institute of Experimental Nuclear Medicine, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Zhekai HuDepartment of Microbiology, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Yabin ZhouDepartment of Microbiology, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Beini ZengDepartment of Microbiology, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Wenjuan LiDepartment of Microbiology, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Jihui JiaDepartment of Microbiology, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Yundong SunDepartment of Microbiology, School of Medicine, Shandong University, Jinan, Shandong, People's Republic of China syd@sdu.edu.cn.
Shandong University · CNGuiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clarithromycin (CLA) is a commonly recommended drug for

Indexed as

Anti-Bacterial AgentsBacterial ProteinsClarithromycinDrug Resistance, BacterialGuanosine PentaphosphateGuanosine TetraphosphateHelicobacter InfectionsHelicobacter pyloriHumansMembrane Transport ProteinsMicrobial Sensitivity TestsMultifunctional EnzymesAnti-Bacterial AgentsBacterial ProteinsClarithromycinGuanosine PentaphosphateGuanosine TetraphosphateMembrane Transport ProteinsMultifunctional Enzymesantibiotic resistanceclarithromycinHelicobacter pyloriSpoTtransporters

Identifiers

PMID28242673
PMCPMC5404559
OpenAlexW2592312616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.