Evidence map›Paper›PMID 28242669›Full record

ArticleAntimicrobial agents and chemotherapy2017

Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling.

Sam Salman, Francisca Baiwog, Madhu Page-Sharp, Susan Griffin, Harin A Karunajeewa, Ivo Mueller, Stephen J Rogerson, Peter M Siba, Kenneth F Ilett, Timothy M E Davis

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Sam SalmanSchool of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia.ORCID 0000-0002-8276-6784
Francisca BaiwogPapua New Guinea Institute of Medical Research, Madang, Papua New Guinea.
Madhu Page-SharpSchool of Pharmacy, Curtin University of Technology, Bentley, Western Australia, Australia.
Susan GriffinPapua New Guinea Institute of Medical Research, Madang, Papua New Guinea.
Harin A KarunajeewaPopulation Health and Immunity, Walter and Eliza Hall Institute, Melbourne, Victoria, Australia.
Ivo MuellerPopulation Health and Immunity, Walter and Eliza Hall Institute, Melbourne, Victoria, Australia.
Stephen J RogersonDepartment of Medicine (RMH), The University of Melbourne, Parkville, Victoria, Australia.
Peter M SibaPapua New Guinea Institute of Medical Research, Madang, Papua New Guinea.
Kenneth F IlettSchool of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia.
Timothy M E DavisSchool of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia tim.davis@uwa.edu.au.ORCID 0000-0003-0749-7411
Papua New Guinea Institute of Medical Research · PGThe University of Western Australia · AUWalter and Eliza Hall Institute of Medical Research · AUCurtin University · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimal dosing of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy remains to be established, particularly when coadministered with azithromycin (AZI). To further characterize SP pharmacokinetics in pregnancy, plasma concentration-time data from 45 nonpregnant and 45 pregnant women treated with SP-AZI (

Indexed as

AdultAntimalarialsAzithromycinDrug CombinationsFemaleHumansInactivation, MetabolicMalariaPregnancyPyrimethamineSulfadoxineSurveys and QuestionnairesAntimalarialsAzithromycinDrug Combinationsfanasil, pyrimethamine drug combinationPyrimethamineSulfadoxineazithromycinmalariapharmacokineticspopulation pharmacokineticspregnancysulfadoxine-pyrimethamine

Identifiers

PMID28242669
PMCPMC5404578
OpenAlexW2592895699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.