Evidence map›Paper›PMID 28242611›Full record

ArticleDevelopment (Cambridge, England)2017

The role of variant histone H2AV in

Melina Grigorian, Heather DeBruhl, Joseph S Lipsick

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Melina GrigorianDepartments of Pathology, Genetics, and Biology, Stanford University, Stanford, CA 94305-5323, USA.
Heather DeBruhlDepartments of Pathology, Genetics, and Biology, Stanford University, Stanford, CA 94305-5323, USA.
Joseph S LipsickDepartments of Pathology, Genetics, and Biology, Stanford University, Stanford, CA 94305-5323, USA lipsick@stanford.edu.ORCID 0000-0001-9231-571X
Stanford University · US

Funding

INSTITUTIONAL TRAINING GRANT IN GENOME SCIENCET32HG000044 · NHGRI · STANFORD UNIVERSITY · PI MICHAEL P. SNYDER · 1995 to 2026
$32.2M
TUMOR BIOLOGYT32CA009151 · NCI · STANFORD UNIVERSITY · PI CLEARY, MICHAEL L · 1985 to 2014
$5.5M
Biology of the Myb-MuvB Oncoprotein-Tumor Suppressor Protein ComplexR01CA128836 · NCI · STANFORD UNIVERSITY · PI LIPSICK, JOSEPH STEVEN · 2007 to 2016
$2.6M
NCI NIH HHS R01 CA128836NCI NIH HHS T32 CA009151NHGRI NIH HHS T32 HG000044
6 · The paper itself

Abstract

Replication-independent histone variants can replace the canonical replication-dependent histones. Vertebrates have multiple H2A variant histones, including H2AZ and H2AX that are present in most eukaryotes. H2AZ regulates transcriptional activation as well as the maintenance of gene silencing, while H2AX is important in DNA damage repair. The fruit fly

Indexed as

HematopoiesisAmino Acid MotifsAmino Acid SequenceAnimalsCell DifferentiationDrosophila melanogasterDrosophila ProteinsGene Knockdown TechniquesHemocytesHistonesHomozygoteLarvaLymph NodesMutationPhenotypePhosphorylationDrosophila ProteinsHis2Av protein, DrosophilaHistonesRecombinant ProteinsDrosophilaH2AVHematopoiesisVariant histone

Identifiers

PMID28242611
PMCPMC5399662
OpenAlexW2591736682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.