Evidence map›Paper›PMID 28242610›Full record

ArticleDevelopment (Cambridge, England)2017

Stomach curvature is generated by left-right asymmetric gut morphogenesis.

Adam Davis, Nirav M Amin, Caroline Johnson, Kristen Bagley, H Troy Ghashghaei, Nanette Nascone-Yoder

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Mechanobiology of vertebrate gut morphogenesis.Current opinion in genetics & development · 2020
    Review
  10. Intrinsic cellular chirality regulates left-right symmetry breaking during cardiac looping.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  11. Review
  12. Article
  13. Chick midgut morphogenesis.The International journal of developmental biology · 2018
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adam DavisDepartment of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.
Nirav M AminDepartment of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.
Caroline JohnsonDepartment of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.
Kristen BagleyDepartment of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.
H Troy GhashghaeiDepartment of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.
Nanette Nascone-YoderDepartment of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA nmnascon@ncsu.edu.ORCID 0000-0003-1301-5298

Funding

TRAINING IN BIOCHEMICAL AND ENVIRONMENTAL TOXICOLOGYT32ES007046 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Seth William Kullman · 1985 to 2026
$5.1M
Transcriptional regulation of aging in the adult neural stem cell nicheR01NS062182 · NINDS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI GHASHGHAEI, HOOMAN TROY · 2010 to 2014
$1.6M
Ahead of the Curve: Mechanisms of Left-Right Asymmetric Stomach MorphogenesisR01HD095937 · NICHD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI NASCONE-YODER, NANETTE M · 2018 to 2022
$1.5M
Pitx2 and Wnt/PCP signaling in left-right asymmetric gut morphogenesisR01DK085300 · NIDDK · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI NASCONE-YODER, NANETTE M · 2010 to 2014
$1.5M
Seq-ing the etiology of birth defects in a new frog model, Lepidobatrachus laevisR21OD017963 · OD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI NASCONE-YODER, NANETTE M · 2014 to 2015
$552k
NICHD NIH HHS R01 HD095937NIDDK NIH HHS R01 DK085300NIEHS NIH HHS T32 ES007046NIH HHS R21 OD017963NINDS NIH HHS R01 NS062182
6 · The paper itself

Abstract

Left-right (LR) asymmetry is a fundamental feature of internal anatomy, yet the emergence of morphological asymmetry remains one of the least understood phases of organogenesis. Asymmetric rotation of the intestine is directed by forces outside the gut, but the morphogenetic events that generate anatomical asymmetry in other regions of the digestive tract remain unknown. Here, we show in mouse and

Indexed as

Body PatterningAnimalsEndodermEpitheliumHomeobox Protein PITX2Homeodomain ProteinsMiceRotationSignal TransductionStomachTranscription FactorsXenopusHomeobox Protein PITX2Homeodomain ProteinsTranscription FactorsAsymmetryGutLeft-rightMorphogenesisMousePitx2StomachXenopus

Identifiers

PMID28242610
PMCPMC5399665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.