ArticleNeurotoxicology and teratology2017
Prenatal tobacco exposure, maternal postnatal nicotine dependence and adolescent risk for nicotine dependence: Birth cohort study.
Article in Neurotoxicology and teratology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Black Father's Influence on Adverse Pregnancy Outcomes in the United States: A Narrative Synthesis of Literature.American journal of men's healthPooled it
- Caregiving Environmental Risk and Aggression From Infancy to Adolescence in a High-Risk Sample: An Examination of Between-Family and Within-Family Effects.Aggressive behavior · 2025Article
- A Study on Adolescent Smoking Prevention and Cessation Policies: Based on the Propensity Score Matching-Difference-in-Differences Method.Healthcare (Basel, Switzerland) · 2024Article
- Prenatal Substance Exposure.Annual review of developmental psychology · 2023Article
- Review
- Prenatal and postnatal drug exposure: focus on persistent central effects.Neural regeneration research · 2023Review
- The Understanding of Maternal Smoking among Women who were Smoking or had Quit Smoking during Pregnancy.The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres · 2023Article
- Prenatal nicotine exposure during pregnancy results in adverse neurodevelopmental alterations and neurobehavioral deficits.Advances in drug and alcohol research · 2023Review
- Prenatal nicotine alters development of the laterodorsal tegmentum: Possible role for attention-deficit/hyperactivity disorder and drug dependence.World journal of psychiatry · 2022Review
- Syndemics of Sexually Transmitted Infections in a Sample of Racially Diverse Pregnant Young Women.Maternal and child health journal · 2022Article
- Prenatal exposure to tobacco and cannabis, early cannabis initiation, and daily dual use of combustible cigarettes and cannabis during young adulthood.Addictive behaviors · 2021Article
- Neuroendocrine and immune pathways from pre- and perinatal stress to substance abuse.Neurobiology of stress · 2018Review
- Prenatal exposures to tobacco and cannabis: Associations with adult electronic cigarette use.Drug and alcohol dependence · 2018Article
- Alpha6-Containing Nicotinic Acetylcholine Receptors Mediate Nicotine-Induced Structural Plasticity in Mouse and Human iPSC-Derived Dopaminergic Neurons.Frontiers in pharmacology · 2018Article
- Trajectories of pre- and postnatal co-use of cannabis and tobacco predict co-use and drug use disorders in adult offspring.Neurotoxicology and teratologyArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
aimsThe goals of this study are to determine if there is (a) a threshold effect for prenatal tobacco exposure (PTE) on adolescent risk for nicotine dependence, and (b) an additive effect of PTE and maternal postnatal nicotine dependence on adolescent risk for nicotine dependence.
methodsPregnant women were recruited in their 4th or 5th gestational month and asked about cigarette use during the first trimester. Mothers reported on third trimester cigarette use at delivery. Sixteen years post-partum, mothers and offspring reported on current levels of cigarette use (N=784). Nicotine dependence was assessed in both using a modified Fagerström questionnaire.
resultsBased on the results of a threshold analysis for PTE, four groups were created: threshold PTE only (10+ cigarettes per day), maternal nicotine postnatal dependence with no-low PTE (0-<10 cigarettes per day), threshold PTE+maternal postnatal nicotine dependence, and a referent group with no-low PTE and no maternal postnatal nicotine dependence. Adolescents in the PTE-only group and the PTE+maternal postnatal nicotine dependence group were significantly more likely to be at risk for nicotine dependence than the offspring from the referent group. However, there was no evidence for an additive effect of maternal postnatal nicotine dependence, and maternal nicotine dependence was not a significant predictor of adolescent risk for nicotine dependence in regression models including prenatal tobacco exposure.
conclusionsBivariate analysis revealed a threshold effect for PTE of 10 cigarettes per day. In multivariate analysis, PTE remained significantly related to risk for offspring nicotine dependence, after controlling for maternal postnatal nicotine dependence and other covariates associated with adolescent cigarette use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.