Evidence map›Paper›PMID 28242137›Full record

ArticlePhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)2017

Evaluation of a multi-atlas CT synthesis approach for MRI-only radiotherapy treatment planning.

F Guerreiro, N Burgos, A Dunlop, K Wong, I Petkar, C Nutting, K Harrington, S Bhide, K Newbold, D Dearnaley and 8 more

Abstract readEvaluation Study
In one paragraph

Article in Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  17. Emerging role of MRI in radiation therapy.Journal of magnetic resonance imaging : JMRI · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

F GuerreiroFaculty of Sciences, University of Lisbon, Campo Grande, Portugal; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom. Electronic address: filipaguerreiro23@gmail.com.
N BurgosTranslational Imaging Group, Centre for Medical Imaging Computing, University College London, London, United Kingdom. Electronic address: n.burgos@ucl.ac.uk.
A DunlopRoyal Marsden Hospital, London, United Kingdom.
K WongRoyal Marsden Hospital, London, United Kingdom.
I PetkarRoyal Marsden Hospital, London, United Kingdom.
C NuttingDivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom; Royal Marsden Hospital, London, United Kingdom.
K HarringtonDivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom; Royal Marsden Hospital, London, United Kingdom.
S BhideDivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom; Royal Marsden Hospital, London, United Kingdom.
K NewboldDivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom; Royal Marsden Hospital, London, United Kingdom.
D DearnaleyDivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom; Royal Marsden Hospital, London, United Kingdom.
N M deSouzaDivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom; Royal Marsden Hospital, London, United Kingdom.
V A MorganRoyal Marsden Hospital, London, United Kingdom.
J McClellandCentre for Medical Image Computing, Dept. Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.
S NillDivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.
M J CardosoTranslational Imaging Group, Centre for Medical Imaging Computing, University College London, London, United Kingdom.
S OurselinTranslational Imaging Group, Centre for Medical Imaging Computing, University College London, London, United Kingdom.
U OelfkeDivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom; Royal Marsden Hospital, London, United Kingdom.
A C KnopfDivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.

Funding

Cancer Research UK 10588Cancer Research UK 12518Cancer Research UK 13407Cancer Research UK 16464Cancer Research UK 19727Cancer Research UK 19908Cancer Research UK 21993Medical Research Council G0701533Medical Research Council MC_EX_MR/M009068/1Medical Research Council MR/M009068/1
6 · The paper itself

Abstract

background and purposeComputed tomography (CT) imaging is the current gold standard for radiotherapy treatment planning (RTP). The establishment of a magnetic resonance imaging (MRI) only RTP workflow requires the generation of a synthetic CT (sCT) for dose calculation. This study evaluates the feasibility of using a multi-atlas sCT synthesis approach (sCT MATERIAL AND

methodsThe multi-atlas method was based on pairs of non-rigidly aligned MR and CT images. The sCT

resultsResults showed that both sCTs were suitable to perform clinical dose calculations with mean dose differences less than 1% for both the planning target volume and the organs at risk. However, only the sCT

conclusionsCombining MR delineations with our multi-atlas CT synthesis method could enable MRI-only treatment planning and thus improve the dosimetric and geometric accuracy of the treatment, and reduce the number of imaging procedures.

Indexed as

Atlases as TopicAlgorithmsFeasibility StudiesHumansMagnetic Resonance ImagingMaleOropharyngeal NeoplasmsProstatic NeoplasmsRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedRetrospective StudiesTomography, X-Ray ComputedMRI-only radiotherapy workflowMulti-atlas approachSynthetic CT

Identifiers

PMID28242137
PMCPMC5368286

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.