Evidence map›Paper›PMID 28241914›Full record

ArticleThe Permanente journal2017

Comprehensive Description of Comorbidity for Autism Spectrum Disorder in a General Population.

David Cawthorpe

Open access · bronzeAbstract read
In one paragraph

Article in The Permanente journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
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  5. Assessment of medical morbidities in a rhesus monkey model of naturally occurring low sociality.Autism research : official journal of the International Society for Autism Research · 2021
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  9. Adult neurodevelopmental services in Singapore: A sociodemographic and clinical profile at a tertiary psychiatric hospital.Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists · 2020
    Article
  10. Article
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  12. Effects of CBD-EnrichedFrontiers in neurology · 2019
    Article
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

David CawthorpeAdjunct Professor in the Departments of Psychiatry and Community Health Services at the University of Calgary in Alberta, Canada. cawthord@ucalgary.ca.
Alberta Health Services · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextFew published studies of autism spectrum disorder (ASD) and comorbidity are population based.

objectiveTo describe the comorbidity of ASD and disorders listed in the main classes of the International Classification of Diseases, Ninth Revision (ICD-9) in a general population.

designDirect physician billing data for the city of Calgary, Alberta, Canada, for the treatment of any presenting concern in the Calgary Health Zone (n = 763,449) from 1994 to 2009 were extracted. Diagnosed ICD-9 disorders (independent variable) were grouped into 17 categories using ICD-9 diagnosis codes. ASD (dependent variable) was classified under ICD-9 Code 299. Individuals with and without independent disorder classes were counted by the presence or absence of any ASD. Odds ratios (ORs) and 95% confidence intervals of the association were calculated.

main outcome measuresORs of ASD comorbidities.

resultsAnnual rates of ASD increased 3.9-fold for males and 1.4-fold for females. Diagnosed disorders ranked by OR in the independent ICD-9 categories indicated that males with ASD had overall higher ORs (> 1.0) in 11 main ICD-9 classes, and females with ASD had higher ORs (> 1.0) in 12 main ICD-9 classes. Males with ASD had lower ORs in 4 main ICD-9 disease classes; females with ASD had lower ORs related only to the main class "complications of pregnancy and childbirth." Five main ICD-9 classes were not significant for males or females.

conclusionsPatients with ASD have significant comorbidity of physical disorders. This finding may inform other areas of research and assessment in clinical management.

Indexed as

Autism Spectrum DisorderComorbidityHealth StatusAdolescentAdultAlbertaChildChild, PreschoolFemaleHumansInfantInternational Classification of DiseasesMaleOdds RatioPregnancyPregnancy Complications

Identifiers

PMID28241914
PMCPMC5283790
OpenAlexW2562382014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.