Evidence map›Paper›PMID 28241904›Full record

Observational studyThe Permanente journal2017

Participation in Activities Associated With Quality of Life for Long-Term Survivors of Rectal Cancer.

Carmit Mcmullen, Liyan Liu, Joanna E Bulkley, Mark C Hornbrook, Christopher Wendel, Marcia Grant, Andrea Altschuler, Larissa Kf Temple, Robert S Krouse, Lisa Herrinton

Registry-linked trialOpen access · greenAbstract readObservational Study
In one paragraph

Observational study in The Permanente journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06975098 (A Journey to Balance), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06975098 nacompletednot on this mapstarted 2024, after this paper: background citation

A Journey to Balance: Development and Validation of Individualized Life Balance Intervention for Depression

TypeinterventionalSponsorChung Shan Medical UniversityRan2024 to 2025Enrolled11ConditionsDepression DisordersArmsLife balance intervention group program
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. The association of bowel function, participation in life activities, and quality of life in rectal cancer survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

Carmit McmullenMedical Anthropologist and Investigator in the Science Programs Department at The Center for Health Research in Portland, OR. carmit.mcmullen@kpchr.org.
Liyan LiuSenior Data Consultant for the Division of Research in Oakland, CA. liyan.liu@kp.org.
Joanna E BulkleyResearch Associate at The Center for Health Research in Portland, OR. joanna.e.bulkley@kpchr.org.
Mark C HornbrookChief Scientist at The Center for Health Research in Portland, OR. mark.c.hornbrook@kpchr.org.
Christopher WendelInstructor at the University of Arizona College of Medicine and Arizona Center on Aging in Tucson. cwendel@aging.arizona.edu.
Marcia GrantDistinguished Professor in the Department of Nursing Research and Education at the City of Hope National Medical Center in Duarte, CA. mgrant@coh.org.
Andrea AltschulerResearch Project Manager for the Division of Research in Oakland, CA. andrea.altschuler@kp.org.
Larissa Kf TempleSurgical Oncologist at the Memorial Sloan-Kettering Cancer Center in New York, NY. templel@mskcc.org.
Robert S KrouseInstructor of Surgery at the University of Pennslvania School of Medicine and Chief of Surgery for the CMC Veterans Affairs Medical Center in Philadelphia. robert.krouse@uphs.upenn.edu.
Lisa HerrintonResearch Scientist for the Division of Research in Oakland, CA. lisa.herrinton@kp.org.
Office of the Chief Scientist · ILOregon Health & Science University · USCity Of Hope National Medical Center · USData Management (Italy) · ITMemorial Sloan Kettering Cancer Center · USMinnesota Project · USUniversity of Arizona · USVeterans Health Administration · US

Funding

HR-QOL in Colorectal Cancer Survivors with StomasR01CA106912 · NCI · UNIVERSITY OF ARIZONA · PI HERRINTON, LISA J, KROUSE, ROBERT SCOTT · 2004 to 2013
$3.4M
Predicting final visual acuity following cataract surgeryR01EY027329 · NEI · KAISER FOUNDATION RESEARCH INSTITUTE · PI HERRINTON, LISA J · 2017 to 2018
$743k
NCI NIH HHS R01 CA106912NEI NIH HHS R01 EY027329
6 · The paper itself

Abstract

contextCancer patients' participation in social, recreational, and civic activities is strongly associated with quality of life (QOL), but these activities are not well integrated into cancer survivorship research or interventions.

objectiveTest the hypothesis that for long-term (≥ 5 years) survivors of rectal cancer, clinical factors (type of surgery and bowel function) are associated with long-term participation in activities and that participation in activities is associated with long-term QOL.

designObservational study with longitudinal and cross-sectional components.

main outcome measuresParticipation in activities and QOL. Tumor registry records were used to identify patients and obtain clinical data; surveys assessed participation and QOL. Using general linear models, we analyzed participation in activities in relation to type of surgery and bowel function after adjustment for potential confounders. We analyzed overall QOL relative to participation in activities after adjustment.

resultsA total of 567 rectal cancer survivors completed a mailed questionnaire. Overall response rate was 61%. The type of operation (p < 0.0001), receipt of radiation therapy (p = 0.002), and bowel function (p < 0.0001) were associated with participation in activities. Participation in activities was the strongest predictor of QOL (p < 0.0001), explaining 20% of the variance (R

conclusionThe importance of participation in activities on rectal cancer survivors' QOL is underappreciated. We recommend revising QOL instruments used in cancer care and research to include questions about participation in activities. Interventions should address maintenance of preferred activities and adoption of new, fulfilling activities.

Indexed as

DefecationQuality of LifeRecreationSocial ParticipationSurvivorsAgedAnal CanalCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleOstomyRectal NeoplasmsRectumSurveys and Questionnaires

Identifiers

PMID28241904
PMCPMC5283789
OpenAlexW2561419641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.