ReviewOrphanet journal of rare diseases2017
Yellow nail syndrome: a review.
Review in Orphanet journal of rare diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 150 citations in OpenAlex.
- Thoracic duct stenting as a treatment for chylothorax and chylous ascites in patient with Yellow Nail Syndrome.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2026Article
- Recurrence of Bilateral Pleural Effusions in a Case of Yellow Nail Syndrome 12 Years After Surgical Pleurodesis.Cureus · 2026Article
- Topical Minoxidil and Low-Dose Oral Minoxidil in Onychodystrophy: A Proposed Treatment Algorithm.Journal of cosmetic dermatology · 2026Review
- Yellow nail syndrome: a syndrome with prominent manifest involvement of the respiratory system.BMC pulmonary medicine · 2026Article
- Yellow Nail Syndrome Presenting With a Complete Clinical Triad: A Report of a Rare Case.Cureus · 2026Article
- Article
- Oral Minoxidil Use in Yellow Nail Syndrome: Report of 2 Cases.Skin appendage disorders · 2025Article
- Article
- A 74-Year-Old Man with Massive Ascites: A Case Report of Yellow Nail Syndrome.Reports (MDPI) · 2025Article
- Bucillamine-induced Yellow Nail Syndrome with Chylothorax.Internal medicine (Tokyo, Japan) · 2025Article
- Primary intestinal lymphangiectasia: French National Diagnosis and Care Protocol (PNDS; Protocole National de Diagnostic et de Soins).Orphanet journal of rare diseases · 2025Review
- A diagnostic journey started with yellow nail syndrome (YNS) ended with the Kartagener's syndrome: a rare case report of coexistence of YNS and Kartagener's syndrome.Annals of medicine and surgery (2012) · 2025Article
- Article
- Yellow nail syndrome linked to a mediastinal lipoma: a case report.Journal of medical case reports · 2024Article
- A Case Report on the Trilogy of Yellow Nail Syndrome: Yellow Nails, Pleural Effusion, and Lymphedema.Cureus · 2024Article
- Control of pleural effusion with prednisolone in a patient with yellow nail syndrome: A case report.Experimental and therapeutic medicine · 2024Article
- Vitamins for the Management of Nail Disease: A Literature Review.Skin appendage disorders · 2024Review
- Article
- Tomato Plant-Associated Xanthoderma: Case Report and Review of Exogenous Causes of Yellow Skin.Cureus · 2023Article
- Yellow Nails in a Patient with Chronic Cough and Daily Afternoon Fever.Skin appendage disorders · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Yellow nail syndrome (YNS; OMIM 153300, ORPHA662) is a very rare disorder that almost always occurs after 50 years of age but a juvenile or familial form has also been observed. YNS is diagnosed based on a triad associating yellow nail discoloration, pulmonary manifestations (chronic cough, bronchiectasia, pleural effusion) and lower limb lymphedema. Chronic sinusitis is frequently associated with the triad. YNS etiology remains unknown but a role of lymphatic impairment is usually evoked. YNS is more frequently isolated but may be associated in rare cases with autoimmune diseases, other clinical manifestations implicating lymphatic functions or cancer and, hence, is also considered a paraneoplastic syndrome. YNS management is symptomatic and not codified. YNS can resolve spontaneously. Oral vitamin E alone or even better when associated with triazole antifungals may achieve partial or total disappearance of nail discoloration. Pleural effusion can be treated surgically, with decortication/pleurectomy or pleurodesis. Antibiotic prophylaxis is prescribed for bronchiectasia with chronic sputum production. Lymphedema treatment is based on low-stretch bandages and the wearing of elastic compression garments combined with skin care, exercises and, as needed, manual lymph drainage.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.