Evidence map›Paper›PMID 28241811›Full record

ArticleBMC pregnancy and childbirth2017

The burden of nausea and vomiting during pregnancy: severe impacts on quality of life, daily life functioning and willingness to become pregnant again - results from a cross-sectional study.

Kristine Heitmann, Hedvig Nordeng, Gro C Havnen, Anja Solheimsnes, Lone Holst

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 49 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 3 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06055192 unknown statusnot on this mapstarted 2023, after this paper: background citation

Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland: Survey Purity 2022

TypeobservationalSponsorEffik SARan2023 to 2024Enrolled200ConditionsNausea, Vomiting of PregnancyArmsSurvey
NCT06415084 recruitingnot on this mapstarted 2025, after this paper: background citation

Hyperemesis Gravidarum Prevalence : A Repeated Cross-sectional Population Based Study

TypeobservationalSponsorUniversity Hospital, Clermont-FerrandRan2025 to 2026Enrolled604ConditionsNausea and Vomiting
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 140 citations in OpenAlex.

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  17. Nausea and Vomiting of Pregnancy in Saudi Females: A Cross-Sectional Study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  18. A qualitative exploration of autistic mothers' experiences I: Pregnancy experiences.Autism : the international journal of research and practice · 2023
    Article
  19. Bioavailability of CaribanDrugs in R&D · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kristine HeitmannPharmacoEpidemiology and Drug Safety Research Group, School of Pharmacy, University of Oslo, Oslo, Norway.
Hedvig NordengPharmacoEpidemiology and Drug Safety Research Group, School of Pharmacy, University of Oslo, Oslo, Norway.
Gro C HavnenRegional Medicines Information and Pharmacovigilance Centre (RELIS), Oslo, Norway.
Anja SolheimsnesDepartment of Global Public Health and Primary Care, University of Bergen, P-Box 7804, N-5020, Bergen, Norway.
Lone HolstDepartment of Global Public Health and Primary Care, University of Bergen, P-Box 7804, N-5020, Bergen, Norway. lone.holst@farm.uib.no.ORCID 0000-0003-4775-5892
University of Bergen · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThough nausea and vomiting is very common during pregnancy, no studies have investigated the impact of this condition on the women's daily lives in a Scandinavian population. The aim of this study was to describe the burden of nausea and vomiting during pregnancy (NVP) on global quality of life, daily life functioning and willingness to become pregnant again according to the severity of NVP symptoms.

methodsThis study is a cross-sectional population-based study conducted in Norway. Pregnant women and mothers with children <1 year of age with current or prior NVP were eligible to participate. Data were collected through an anonymous on-line questionnaire accessible from November 10

results712 women with NVP were included in the study. NVP was significantly associated with several characteristics, including daily life functioning, quality of life and willingness to become pregnant again. The negative impact was greater the more severe the symptoms were, although considerable adverse effects were also seen among women with mild and moderate NVP symptoms. Over one fourth of the women with severe NVP considered terminating the pregnancy due to NVP, and three in four considered not to get pregnant again. Severity of NVP remained significantly associated with reduced global quality of life when adjusting for maternal characteristics and illnesses with β (95% CI) = -10.9 (-16.9, -4.9) for severe versus mild NVP.

conclusionsNVP as measured by PUQE had a major impact on various aspects of the women's lives, including global quality of life and willingness to become pregnant again.

Indexed as

Activities of Daily LivingAttitude to HealthQuality of LifeAbortion, InducedAdultCost of IllnessCross-Sectional StudiesFemaleHumansHyperemesis GravidarumMorning SicknessNorwayPregnancySeverity of Illness IndexSurveys and QuestionnairesYoung AdultBurden of illnessHyperemesis gravidarumMorning sicknessNVPPregnancyQuality of lifeTermination of pregnancy

Identifiers

PMID28241811
PMCPMC5329925
OpenAlexW2592377817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.