ArticleBMC genomics2017
Response of microRNAs to cold treatment in the young spikes of common wheat.
Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 89 citations in OpenAlex.
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- Integrative analyses reveal Bna-miR397a-BnaLAC2 as a potential modulator of low-temperature adaptability in Brassica napus L.Plant biotechnology journal · 2025Article
- Genome-wide identification and comprehensive characterization of the ADF gene family inFrontiers in plant science · 2025Article
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- Characterization of tae-miR156(s) and their response to abiotic stress in wheat (Triticum aestivum L.).BMC plant biology · 2024Article
- Bioinformatic Analysis of the BTB Gene Family inPlants (Basel, Switzerland) · 2023Article
- Genome-wide identification and expression analysis of theFrontiers in plant science · 2023Article
- Integrated sRNA-seq and RNA-seq Analyses Reveal a microRNA Regulation Network Involved in Cold Response inGenes · 2022Article
- An Integration of MicroRNA and Transcriptome Sequencing Analysis Reveal Regulatory Roles of miRNAs in Response to Chilling Stress in Wild Rice.Plants (Basel, Switzerland) · 2022Article
- Small RNA and Degradome Deep Sequencing Reveals the Roles of microRNAs in Peanut (Frontiers in plant science · 2022Article
- Identification of long non-coding RNA-microRNA-mRNA regulatory modules and their potential roles in drought stress response in wheat (Frontiers in plant science · 2022Article
- Comparative Physiology and Transcriptome Analysis of Young Spikes in Response to Late Spring Coldness in Wheat (Frontiers in plant science · 2022Article
- Temporal expression study of miRNAs in the crown tissues of winter wheat grown under natural growth conditions.BMC genomics · 2021Article
- The Roles of Temperature-Related Post-Transcriptional Regulation in Cereal Floral Development.Plants (Basel, Switzerland) · 2021Review
- Small RNAs, Degradome, and Transcriptome Sequencing Provide Insights into Papaya Fruit Ripening Regulated by 1-MCP.Foods (Basel, Switzerland) · 2021Article
- Genome-wide profiling of long noncoding RNAs involved in wheat spike development.BMC genomics · 2021Article
- TarDB: an online database for plant miRNA targets and miRNA-triggered phased siRNAs.BMC genomics · 2021Article
- MicroRNAs: Potential Targets for Developing Stress-Tolerant Crops.Life (Basel, Switzerland) · 2021Review
- Article
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicroRNAs (miRNAs) are a class of small non-coding RNAs that play important roles in biotic and abiotic stresses by regulating their target genes. For common wheat, spring frost damage frequently occurs, especially when low temperature coincides with plants at early floral organ differentiation, which may result in significant yield loss. Up to date, the role of miRNAs in wheat response to frost stress is not well understood.
resultsWe report here the sequencing of small RNA transcriptomes from the young spikes that were treated with cold stress and the comparative analysis with those of the control. A total of 192 conserved miRNAs from 105 families and nine novel miRNAs were identified. Among them, 34 conserved and five novel miRNAs were differentially expressed between the cold-stressed samples and the controls. The expression patterns of 18 miRNAs were further validated by quantitative real time polymerase chain reaction (qRT-PCR). Moreover, nearly half of the miRNAs were cross inducible by biotic and abiotic stresses when compared with previously published work. Target genes were predicted and validated by degradome sequencing. Gene Ontology (GO) enrichment analysis showed that the target genes of differentially expressed miRNAs were enriched for response to the stimulus, regulation of transcription, and ion transport functions. Since many targets of differentially expressed miRNAs were transcription factors that are associated with floral development such as ARF, SPB (Squamosa Promoter Binding like protein), MADS-box (MCM1, AG, DEFA and SRF), MYB, SPX (SYG1, Pho81 and XPR1), TCP (TEOSINTE BRANCHED, Cycloidea and PCF), and PPR (PentatricoPeptide Repeat) genes, cold-altered miRNA expression may cause abnormal reproductive organ development.
conclusionAnalysis of small RNA transcriptomes and their target genes provide new insight into miRNA regulation in developing wheat inflorescences under cold stress. MiRNAs provide another layer of gene regulation in cold stress response that can be genetically manipulated to reduce yield loss in wheat.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.