Evidence map›Paper›PMID 28241514›Full record

ArticleToxins2017

Antivenom Evaluation by Electrophysiological Analysis.

Rita Restano-Cassulini, Walter Garcia, Jorge F Paniagua-Solís, Lourival D Possani

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Immunological Responses to Envenomation.Frontiers in immunology · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rita Restano-CassuliniInstituto de Biotecnologia, National Autonomous University of México, Av. Univeresidad 2001, Col. Chamilpa, Cuernavaca 62210, Morelos, Mexico. rita@ibt.unam.mx.
Walter GarciaInstituto Bioclón S.A. de C.V., Calle Miguel Laurent 427, Del. Benito Juarez, Ciudad de México 03100, Mexico. wgarcia@silanes.com.mx.
Jorge F Paniagua-SolísLaboratorios Silanes, S.A. de C.V., Amores 1304, Colonia del Valle, Ciudad de México 03100, Mexico. jpaniagua@laboratoriosilanes.es.
Lourival D PossaniInstituto de Biotecnologia, National Autonomous University of México, Av. Univeresidad 2001, Col. Chamilpa, Cuernavaca 62210, Morelos, Mexico. possani@ibt.unam.mx.
Universidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scorpion stings on humans are medically relevant because they may contain toxins that specifically target ion channels. During antivenom production, pharmaceutical companies must use a large number of experimental animals to ensure the antivenom's efficacy according to pharmacopeia methods. Here we present an electrophysiological alternative for the evaluation of horse antivenoms produced against two species of Moroccan scorpions:

Indexed as

AnimalsAnimal Testing AlternativesAntiveninsElectrophysiological PhenomenaHEK293 CellsHumansScorpionsScorpion VenomsSodium ChannelsAntiveninsScorpion VenomsSodium Channelsantivenomelectrophysiologyhorse immunoglobulinhuman ion channels scorpion venomspatch-clampsodium channel

Identifiers

PMID28241514
PMCPMC5371829
OpenAlexW2590014847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.