ArticleJournal of biomechanical engineering2017
Collagen Organization in Facet Capsular Ligaments Varies With Spinal Region and With Ligament Deformation.
Article in Journal of biomechanical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Anatomy and biomechanics of posterior ligamentous complex of the human spine: a narrative review.Surgical and radiologic anatomy : SRA · 2025Review
- Residual Strain and Joint Pressurization Maintain Collagen Tension for On-Joint Lumbar Facet Capsular Ligaments.Journal of biomechanical engineering · 2024Article
- Cervical facet capsular ligament mechanics: Estimations based on subject-specific anatomy and kinematics.JOR spine · 2023Article
- Characterization of the L4/L5 rat facet capsular ligament macromechanical and microstructural responses to tensile failure loading.Journal of biomechanics · 2023Article
- The Lumbar Facet Capsular Ligament Becomes More Anisotropic and the Fibers Become Stiffer With Intervertebral Disc and Facet Joint Degeneration.Journal of biomechanical engineering · 2023Article
- In vivo assessment of mitral valve leaflet remodelling following myocardial infarction.Scientific reports · 2022Article
- In Situ Lumbar Facet Capsular Ligament Strains Due to Joint Pressure and Residual Strain.Journal of biomechanical engineering · 2022Article
- Degeneration of the lumbar spine and its relation to the expression of collagen and elastin in facet joint capsules and ligament flavum.Acta orthopaedica et traumatologica turcica · 2022Article
- Intra-articular MMP-1 in the spinal facet joint induces sustained pain and neuronal dysregulation in the DRG and spinal cord, and alters ligament kinematics under tensile loading.Frontiers in bioengineering and biotechnology · 2022Article
- Local tissue heterogeneity may modulate neuronal responses via altered axon strain fields: insights about innervated joint capsules from a computational model.Biomechanics and modeling in mechanobiology · 2021Article
- Through-thickness regional variation in the mechanical characteristics of the lumbar facet capsular ligament.Biomechanics and modeling in mechanobiology · 2021Article
- Asymmetric in-plane shear behavior of isolated cadaveric lumbar facet capsular ligaments: Implications for subject specific biomechanical models.Journal of biomechanics · 2020Article
- Effects of Collagen Heterogeneity on Myocardial Infarct Mechanics in a Multiscale Fiber Network Model.Journal of biomechanical engineering · 2019Article
- Multiscale model of fatigue of collagen gels.Biomechanics and modeling in mechanobiology · 2019Article
- Multiscale modelling of the human lumbar facet capsular ligament: analysing spinal motion from the joint to the neurons.Journal of the Royal Society, Interface · 2018Article
- The role of the facet capsular ligament in providing spinal stability.Computer methods in biomechanics and biomedical engineering · 2018Article
- Repeated High Rate Facet Capsular Stretch at Strains That are Below the Pain Threshold Induces Pain and Spinal Inflammation With Decreased Ligament Strength in the Rat.Journal of biomechanical engineering · 2018Article
- Multi-resolution geometric modeling of the mitral heart valve leaflets.Biomechanics and modeling in mechanobiology · 2018Article
- Collagen organization regulates stretch-initiated pain-related neuronal signals in vitro: Implications for structure-function relationships in innervated ligaments.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018Article
- Multiscale mechanics of the cervical facet capsular ligament, with particular emphasis on anomalous fiber realignment prior to tissue failure.Biomechanics and modeling in mechanobiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
The spinal facet capsular ligament (FCL) is primarily comprised of heterogeneous arrangements of collagen fibers. This complex fibrous structure and its evolution under loading play a critical role in determining the mechanical behavior of the FCL. A lack of analytical tools to characterize the spatial anisotropy and heterogeneity of the FCL's microstructure has limited the current understanding of its structure-function relationships. Here, the collagen organization was characterized using spatial correlation analysis of the FCL's optically obtained fiber orientation field. FCLs from the cervical and lumbar spinal regions were characterized in terms of their structure, as was the reorganization of collagen in stretched cervical FCLs. Higher degrees of intra- and intersample heterogeneity were found in cervical FCLs than in lumbar specimens. In the cervical FCLs, heterogeneity was manifested in the form of curvy patterns formed by collections of collagen fibers or fiber bundles. Tensile stretch, a common injury mechanism for the cervical FCL, significantly increased the spatial correlation length in the stretch direction, indicating an elongation of the observed structural features. Finally, an affine estimation for the change of correlation length under loading was performed which gave predictions very similar to the actual values. These findings provide structural insights for multiscale mechanical analyses of the FCLs from various spinal regions and also suggest methods for quantitative characterization of complex tissue patterns.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.