Evidence map›Paper›PMID 28241215›Full record

Trial reportAnnals of internal medicine2017

Effectiveness of an Internet-Delivered Exercise and Pain-Coping Skills Training Intervention for Persons With Chronic Knee Pain: A Randomized Trial.

Kim L Bennell, Rachel Nelligan, Fiona Dobson, Christine Rini, Francis Keefe, Jessica Kasza, Simon French, Christina Bryant, Andrew Dalwood, J Haxby Abbott and 1 more

3 registry-linked trialsAbstract readPragmatic Clinical TrialRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Annals of internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 149 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
149citing papers in PubMed, 14 pooled it
26.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04199416 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Effectiveness of an Interactive, Multi-functional Mobile App-based Technology in Endogenous Healthcare for Individuals With or at Risk of Knee Osteoarthritis: A 12-month Randomized Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2021 to 2023Enrolled320ConditionsKnee Pain/Osteoarthritis, Digital HealthArmsmRehab app, Sham app
NCT04814992 nacompletednot on this mapstarted 2020, after this paper: background citation

Pre-op CBT to Reduce the Risk for Development of Chronic Post-surgical Pain in Patients Undergoing Total Knee Arthroplasty

TypeinterventionalSponsorUniversity of PennsylvaniaRan2020 to 2023Enrolled54ConditionsChronic Post-Surgical PainArmsComputer-Assisted Preoperative CBT Intervention (PAINTrainer)
NCT07302958 narecruitingnot on this mapstarted 2026, after this paper: background citation

Telerehabilitation, Face-to-Face Exercises, and a Mixed Model in Chronic Non-Specific Neck Pain

TypeinterventionalSponsorCairo UniversityRan2026 to 2026Enrolled68ConditionsChronic Non-specific Neck PainArmsReal-Time Video-Guided Neck Exercises (Tele-Rehabilitation), In-Person Supervised Neck Exercises (Face-to-Face), Hybrid Tele-Rehabilitation and In-Person Exercises (Mixed Model)
3 · Its place in the literature

Who cites it

149 citing papers in PubMed, 14 syntheses or guidelines pooled it, 305 citations in OpenAlex.

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  19. Impact of Monthly Community Follow-Ups in Knee Osteoarthritis Management for Elderly Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025
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89 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Kim L BennellFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Rachel NelliganFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Fiona DobsonFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Christine RiniFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Francis KeefeFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Jessica KaszaFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Simon FrenchFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Christina BryantFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Andrew DalwoodFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
J Haxby AbbottFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Rana S HinmanFrom the University of Melbourne, Monash University, Royal Women's Hospital, and Physioworks Health Group, Melbourne, Victoria, Australia; UNC Gillings School of Global Public Health, Chapel Hill, North Carolina; Duke University, Durham, North Carolina; Queen's University, Kingston, Ontario, Canada; and Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Queen's University · CAUniversity of Otago · NZDuke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEffective, accessible biopsychosocial treatments are needed to manage chronic knee pain on a population level.

objectiveTo evaluate the effectiveness of Internet-delivered, physiotherapist-prescribed home exercise and pain-coping skills training (PCST).

designPragmatic parallel-group randomized, controlled trial. (Australian New Zealand Clinical Trials Registry: ACTRN12614000243617).

settingCommunity (Australia). PATIENTS: 148 persons aged 50 years or older with chronic knee pain.

interventionThe intervention was delivered via the Internet and included educational material, 7 videoconferencing (Skype [Microsoft]) sessions with a physiotherapist for home exercise, and a PCST program over 3 months. The control was Internet-based educational material. MEASUREMENTS: Primary outcomes were pain during walking (11-point numerical rating scale) and physical function (Western Ontario and McMaster Universities Osteoarthritis Index) at 3 months. Secondary outcomes were knee pain, quality of life, global change (overall, pain, and functional status), arthritis self-efficacy, coping, and pain catastrophizing. Outcomes were also measured at 9 months.

resultsOf participants enrolled, 139 (94%) completed primary outcome measures at 3 months and 133 (90%) completed secondary outcome measures at 9 months; multiple imputation was used for missing data. The intervention group reported significantly more improvement in pain (mean difference, 1.6 units [95% CI, 0.9 to 2.3 units]) and physical function (mean difference, 9.3 units [CI, 5.9 to 12.7 units]) than the control group at 3 months, and improvements were sustained at 9 months (mean differences, 1.1 units [CI, 0.4 to 1.8 units] and 7.0 units [CI, 3.4 to 10.5 units], respectively). Intervention participants showed significantly more improvement in most secondary outcomes than control participants. At both time points, significantly more intervention participants reported global improvements. LIMITATION: Participants were unblinded.

conclusionFor persons with chronic knee pain, Internet-delivered, physiotherapist-prescribed exercise and PCST provide clinically meaningful improvements in pain and function that are sustained for at least 6 months. PRIMARY FUNDING SOURCE: National Health and Medical Research Council.

Indexed as

Adaptation, PsychologicalInternetAftercareChronic PainExercise TherapyFemaleHumansMaleMiddle AgedOsteoarthritis, KneePain MeasurementPatient Education as TopicTreatment Outcome

Identifiers

PMID28241215
OpenAlexW2589389097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.