Evidence map›Paper›PMID 28241185›Full record

Trial reportAnnals of internal medicine2017

Maintenance of Weight Loss After Initiation of Nutrition Training: A Randomized Trial.

Corrine I Voils, Maren K Olsen, Jennifer M Gierisch, Megan A McVay, Janet M Grubber, Leslie Gaillard, Jamiyla Bolton, Matthew L Maciejewski, Elizabeth Strawbridge, William S Yancy

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Annals of internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01357551 (Maintenance After Initiation of Nutrition TrAINing), which is not on this map. Cited by 30 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01357551 nacompletednot on this map

Maintenance After Initiation of Nutrition TrAINing (MAINTAIN)

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2012 to 2015Enrolled222ConditionsObesityArmsMaintenance intervention
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  3. A systematic review of inequalities in the uptake of, adherence to, and effectiveness of behavioral weight management interventions in adults.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Corrine I VoilsFrom Durham Veterans Affairs Medical Center, Duke University Medical Center, and Duke University Diet and Fitness Center, Durham, North Carolina.
Maren K OlsenFrom Durham Veterans Affairs Medical Center, Duke University Medical Center, and Duke University Diet and Fitness Center, Durham, North Carolina.
Jennifer M GierischFrom Durham Veterans Affairs Medical Center, Duke University Medical Center, and Duke University Diet and Fitness Center, Durham, North Carolina.
Megan A McVayFrom Durham Veterans Affairs Medical Center, Duke University Medical Center, and Duke University Diet and Fitness Center, Durham, North Carolina.
Janet M GrubberFrom Durham Veterans Affairs Medical Center, Duke University Medical Center, and Duke University Diet and Fitness Center, Durham, North Carolina.
Leslie GaillardFrom Durham Veterans Affairs Medical Center, Duke University Medical Center, and Duke University Diet and Fitness Center, Durham, North Carolina.
Jamiyla BoltonFrom Durham Veterans Affairs Medical Center, Duke University Medical Center, and Duke University Diet and Fitness Center, Durham, North Carolina.
Matthew L MaciejewskiFrom Durham Veterans Affairs Medical Center, Duke University Medical Center, and Duke University Diet and Fitness Center, Durham, North Carolina.
Elizabeth StrawbridgeFrom Durham Veterans Affairs Medical Center, Duke University Medical Center, and Duke University Diet and Fitness Center, Durham, North Carolina.
William S YancyFrom Durham Veterans Affairs Medical Center, Duke University Medical Center, and Duke University Diet and Fitness Center, Durham, North Carolina.

Funding

Increasing uptake of behavioral weight loss programs among primary care patientsK23HL127334 · NHLBI · UNIVERSITY OF FLORIDA · PI MCVAY, MEGAN APPERSON · 2015 to 2019
$805k
Maintenance After Initiation of Nutrition TrAINing (MAINTAIN)I01HX000690 · VA · DURHAM VA MEDICAL CENTER · PI VOILS, CORRINE IONE, YANCY, WILLIAM S. · 2013 to 2013
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HSRD VA I01 HX000690NHLBI NIH HHS K23 HL127334
6 · The paper itself

Abstract

backgroundWeight regain after successful weight loss interventions is common.

objectiveTo establish the efficacy of a weight loss maintenance program compared with usual care in obese adults.

design2-group, parallel, randomized trial stratified by initial weight loss (<10 kg vs. ≥10 kg), conducted from 20 August 2012 to 18 December 2015. Outcome assessors were blinded to treatment assignment. (ClinicalTrials.gov: NCT01357551).

setting3 primary care clinics at the Veterans Affairs Medical Center in Durham and Raleigh, North Carolina. PATIENTS: Obese outpatients (body mass index ≥30 kg/m2) who lost 4 kg or more of body weight during a 16-week, group-based weight loss program.

interventionThe maintenance intervention, delivered primarily by telephone, addressed satisfaction with outcomes, relapse-prevention planning, self-monitoring, and social support. Usual care involved no contact except for study measurements. MEASUREMENTS: Primary outcome was mean weight regain at week 56. Secondary outcomes included self-reported caloric intake, walking, and moderate physical activity.

resultsOf 504 patients in the initial program, 222 lost at least 4 kg of body weight and were randomly assigned to maintenance (n = 110) or usual care (n = 112). Retention was 85%. Most patients were middle-aged white men. Mean weight loss during initiation was 7.2 kg (SD, 3.1); mean weight at randomization was 103.6 kg (SD, 20.4). Estimated mean weight regain was statistically significantly lower in the intervention (0.75 kg) than the usual care (2.36 kg) group (estimated mean difference, 1.60 kg [95% CI, 0.07 to 3.13 kg]; P = 0.040). No statistically significant differences in secondary outcomes were seen at 56 weeks. No adverse events directly attributable to the intervention were observed. LIMITATIONS: Results may not generalize to other settings or populations. Dietary intake and physical activity were self-reported. Duration was limited to 56 weeks.

conclusionAn intervention focused on maintenance-specific strategies and delivered in a resource-conserving way modestly slowed the rate of weight regain in obese adults. PRIMARY FUNDING SOURCE: Veterans Affairs Health Services Research and Development Service.

Indexed as

Weight LossWeight Reduction ProgramsDirective CounselingExerciseFemaleFollow-Up StudiesHealth Care CostsHealth ExpendituresHumansMaleMiddle AgedObesityPatient SatisfactionSecondary PreventionSocial SupportTreatment Outcome

Identifiers

PMID28241185
PMCPMC5483942

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.