Evidence map›Paper›PMID 28241019›Full record

ArticlePloS one2017

Affordability of medicines in the European Union.

Tomasz Zaprutko, Dorota Kopciuch, Krzysztof Kus, Piotr Merks, Monika Nowicka, Izabela Augustyniak, Elżbieta Nowakowska

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
27.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  6. Availability and affordability of cardiovascular medicines in a major city of Afghanistan in 2020.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2022
    Article
  7. Article
  8. Utilization, Cost, and Affordability of Antihypertensive Therapy in Bulgaria.Iranian journal of pharmaceutical research : IJPR · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tomasz ZaprutkoDepartment of Pharmacoeconomics and Social Pharmacy, Poznan University of Medical Sciences, Poznań, Poland.
Dorota KopciuchDepartment of Pharmacoeconomics and Social Pharmacy, Poznan University of Medical Sciences, Poznań, Poland.
Krzysztof KusDepartment of Pharmacoeconomics and Social Pharmacy, Poznan University of Medical Sciences, Poznań, Poland.
Piotr MerksDepartment of Pharmaceutical Technology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Toruń, Poland.
Monika NowickaStudent Scientific Society, Department of Pharmacoeconomics and Social Pharmacy, Poznan University of Medical Sciences, Poznań, Poland.
Izabela AugustyniakStudent Scientific Society, Department of Pharmacoeconomics and Social Pharmacy, Poznan University of Medical Sciences, Poznań, Poland.
Elżbieta NowakowskaDepartment of Pharmacoeconomics and Social Pharmacy, Poznan University of Medical Sciences, Poznań, Poland.
Poznan University of Medical Sciences · PLNicolaus Copernicus University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedications and their prices are key issues for healthcare. Although access to medicines at affordable prices had been specified as a key objective of the European Health Policy, it seems that these goals have not been achieved. Therefore, we attempted an evaluation of affordability of selected medicines at full prices.

methodsThe analysis concerned 2012 and was conducted between 2013 and 2015 in all the European Union (EU) countries divided into 3 groups depending on the date of their accession to the EU. Finally, we considered 9 originators used in the treatment of schizophrenia and multiple sclerosis. Information on drug prices were collected from pharmacies. Participation in the study was voluntary and anonymous in order to avoid accusations of advertising. To evaluate affordability, several factors were used (e.g. minimum earnings and Gini coefficient). Due to unavailability in some countries, the exact number of analyzed medicines varies.

resultsDrug prices vary significantly between EU Member States. Almost eleven fold difference was observed between Germany (EUR 1451.17) and Croatia (EUR 132.77) in relation to Interferone beta-1a 22 μg. Generally, prices were the highest in Germany. The cheapest drugs were found in various countries but never in the poorest ones like Bulgaria or Romania. Discrepancies in wages were observed too (the smallest minimum wage was EUR 138.00 in Bulgaria and the highest EUR 1801.00 in Luxembourg). Full price of olanzapine 5mg, however, was higher in Bulgaria (EUR 64.53) than, for instance, in Belgium (EUR 37.26).

conclusionsAnalyzed medications are still unaffordable for many citizens of the EU. Besides, access to medicines is also impaired e.g. due to parallel trade. Unaffordability of medications may lead to the patients' non-compliance and therefore to increased direct and indirect costs of treatment. Common European solutions are needed to achieve a real affordability and accessibility of medications.

Indexed as

Drug and Narcotic ControlDrug CostsBelgiumBulgariaCommerceCroatiaData CollectionDrugs, EssentialEuropean UnionGermanyHealth Services AccessibilityHumansIncomeLuxembourgMultiple SclerosisPharmaciesDrugs, Essential

Identifiers

PMID28241019
PMCPMC5328386
OpenAlexW2592980711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.