ArticleRadiation research2017
The Causal Relationship between DNA Damage Induction in Bovine Lymphocytes and the Fukushima Nuclear Power Plant Accident.
Article in Radiation research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- Pilot clinical study of ascorbic acid treatment in cardiac catheterization.Journal of radiation research · 2019Trial
- Investigation of DNA Damage and Apoptosis in Bovine Ocular Squamous Cell Carcinoma.Veterinary medicine and science · 2025Article
- Senescence-Associated Heterochromatin Foci Suppress γ-H2AX Focus Formation Induced by Radiation Exposure.International journal of molecular sciences · 2024Article
- Review
- Nuclear and Radiological Emergencies: Biological Effects, Countermeasures and Biodosimetry.Antioxidants (Basel, Switzerland) · 2022Review
- Analysis of whole-blood antioxidant capacity after chronic and localized irradiation using the i-STrap method.Journal of radiation research · 2022Article
- A review of the impact on the ecosystem after ionizing irradiation: wildlife population.International journal of radiation biology · 2022Review
- Chromosomal Aberrations in Cattle.Genes · 2021Review
- Article
- Internal exposure rate conversion coefficients and absorbed fractions of mouse for 137Cs, 134Cs and 90Sr contamination in body.Journal of radiation research · 2020Article
- DNA damage response in peripheral mouse blood leukocytes in vivo after variable, low-dose rate exposure.Radiation and environmental biophysics · 2020Article
- Overwintering States of the Pale Grass Blue ButterflyInsects · 2019Article
- Tolerance of High Oral Doses of Nonradioactive and Radioactive Caesium Chloride in the Pale Grass Blue ButterflyInsects · 2019Article
- Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and spleen mononuclear cells in vivo following Cesium-137 administration.BMC molecular and cell biology · 2019Article
- Developmental and hemocytological effects of ingesting Fukushima's radiocesium on the cabbage white butterfly Pieris rapae.Scientific reports · 2019Article
- Decreased blood cell counts were not observed in cattle living in the "difficult-to-return zone" of the Fukushima nuclear accident.Animal science journal = Nihon chikusan Gakkaiho · 2019Article
- Haematological analysis of Japanese macaques (Macaca fuscata) in the area affected by the Fukushima Daiichi Nuclear Power Plant accident.Scientific reports · 2018Article
- Estimation of concentration of radionuclides in skeletal muscle from blood, based on the data from abandoned animals in Fukushima.Animal science journal = Nihon chikusan Gakkaiho · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 7 institutions in 2 countries.
Funding
Abstract
The Fukushima Daiichi Nuclear Power Plant (FNPP) accident, the largest nuclear incident since the 1986 Chernobyl disaster, occurred when the plant was hit by a tsunami triggered by the Great East Japan Earthquake on March 11, 2011. The subsequent uncontrolled release of radioactive substances resulted in massive evacuations in a 20-km zone. To better understand the biological consequences of the FNPP accident, we have been measuring DNA damage levels in cattle in the evacuation zone. DNA damage was evaluated by assessing the levels of DNA double-strand breaks in peripheral blood lymphocytes by immunocytofluorescence-based quantification of γ-H2AX foci. A greater than two-fold increase in the fraction of damaged lymphocytes was observed in all animal cohorts within the evacuation zone, and the levels of DNA damage decreased slightly over the 700-day sample collection period. While the extent of damage appeared to be independent of the distance from the accident site and the estimated radiation dose from radiocesium, we observed age-dependent accumulation of DNA damage. Thus, this study, which was the first to evaluate the biological impact of the FNPP accident utilizing the γ-H2AX assays, indicated the causal relation between high levels of DNA damage in animals living in the evacuation zone and the FNPP accident.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.