Evidence map›Paper›PMID 28240398›Full record

ArticleJournal of veterinary internal medicine2017

Standardization of a Videofluoroscopic Swallow Study Protocol to Investigate Dysphagia in Dogs.

R A Harris, M E Grobman, M J Allen, J Schachtel, N E Rawson, B Bennett, J Ledyayev, B Hopewell, J R Coates, C R Reinero and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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  17. A One Health review of aerodigestive disease in dogs.Journal of veterinary internal medicine
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

R A HarrisDepartment of Communication Science and Disorders, University of Missouri, Columbia, MO.
M E GrobmanDepartment of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, Columbia, MO.
M J AllenDepartment of Otolaryngology-Head and Neck Surgery, University of Missouri School of Medicine, Columbia, MO.
J SchachtelDepartment of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, Columbia, MO.
N E RawsonAFB International, St. Charles, MO.
B BennettAFB International, St. Charles, MO.
J LedyayevAFB International, St. Charles, MO.
B HopewellDepartment of Otolaryngology-Head and Neck Surgery, University of Missouri School of Medicine, Columbia, MO.
J R CoatesDepartment of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, Columbia, MO.
C R ReineroDepartment of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, Columbia, MO.
T E LeverDepartment of Otolaryngology-Head and Neck Surgery, University of Missouri School of Medicine, Columbia, MO.
Missouri College · USUniversity of Missouri · USSt. Charles Hospital · USMonell Chemical Senses Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVideofluoroscopic swallow study (VFSS) is the gold standard for diagnosis of dysphagia in veterinary medicine but lacks standardized protocols that emulate physiologic feeding practices. Age impacts swallow function in humans but has not been evaluated by VFSS in dogs. HYPOTHESIS/

objectivesTo develop a protocol with custom kennels designed to allow free-feeding of 3 optimized formulations of contrast media and diets that address limitations of current VFSS protocols. We hypothesized that dogs evaluated by a free-feeding VFSS protocol would show differences in objective swallow metrics based on age. ANIMALS: Healthy juvenile, adult, and geriatric dogs (n = 24).

methodsProspective, experimental study. Custom kennels were developed to maintain natural feeding behaviors during VFSS. Three food consistencies (thin liquid, pureed food, and dry kibble) were formulated with either iohexol or barium to maximize palatability and voluntary prehension. Dogs were evaluated by 16 swallow metrics and compared across age groups.

resultsDevelopment of a standardized VFSS protocol resulted in successful collection of swallow data in healthy dogs. No significant differences in swallow metrics were observed among age groups. Substantial variability was observed in healthy dogs when evaluated under these physiologic conditions. Features typically attributed to pathologic states, such as gastric reflux, were seen in healthy dogs. CONCLUSIONS AND CLINICAL IMPORTANCE: Development of a VFSS protocol that reflects natural feeding practices may allow emulation of physiology resulting in clinical signs of dysphagia. Age did not result in significant changes in swallow metrics, but additional studies are needed, particularly in light of substantial normal variation.

Indexed as

DeglutitionAge FactorsAnimalsBariumContrast MediaDeglutition DisordersDogsFluoroscopyIohexolProspective StudiesReference StandardsVideo RecordingBariumContrast MediaIohexolAspirationBariumFree-feedingIohexolReflux

Identifiers

PMID28240398
PMCPMC5354069
OpenAlexW2594438570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.