ArticleEpidemiology and infection2017
Zika in Rio de Janeiro: Assessment of basic reproduction number and comparison with dengue outbreaks.
Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and evaluation of Zika virus forecasting and prediction research during a public health emergency of international concern.PLoS neglected tropical diseases · 2019Pooled it
- Dengue virus introduction and 2025 outlook: scenario-based evaluation of vaccination impact using mathematical modeling.Cadernos de saude publica · 2026Article
- Analysis of a diffusive two-strain malaria model with the carrying capacity of the environment for mosquitoes.Infectious Disease Modelling · 2024Article
- Infection Prevention and Control Strategies According to the Type of Multidrug-Resistant Bacteria andAntibiotics (Basel, Switzerland) · 2024Review
- Spatial analysis of Dengue through the reproduction numbers relating to socioeconomic features: Case studies on two Brazilian urban centers.Infectious Disease Modelling · 2024Article
- Seroprevalence of Zika in Brazil stratified by age and geographic distribution.Epidemiology and infection · 2023Article
- Epidemiological and genomic investigation of chikungunya virus in Rio de Janeiro state, Brazil, between 2015 and 2018.PLoS neglected tropical diseases · 2023Article
- Long-term projections of the impacts of warming temperatures on Zika and dengue risk in four Brazilian cities using a temperature-dependent basic reproduction number.PLoS neglected tropical diseases · 2023Article
- Occurrence of yellow fever outbreaks in a partially vaccinated population: An analysis of the effective reproduction number.PLoS neglected tropical diseases · 2022Article
- RHuman vaccines & immunotherapeutics · 2021Review
- Past and future epidemic potential of chikungunya virus in Australia.PLoS neglected tropical diseases · 2021Article
- Why Did ZIKV Perinatal Outcomes Differ in Distinct Regions of Brazil? An Exploratory Study of Two Cohorts.Viruses · 2021Article
- Surveillance and Epidemiology of Dengue in Medellín, Colombia from 2009 to 2017.The American journal of tropical medicine and hygiene · 2021Article
- Leveraging multiple data types to estimate the size of the Zika epidemic in the Americas.PLoS neglected tropical diseases · 2020Article
- Estimation of mosquito-borne and sexual transmission of Zika virus in Australia: Risks to blood transfusion safety.PLoS neglected tropical diseases · 2020Article
- Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro.PloS one · 2020Article
- Article
- Sex-Specific Asymmetrical Attack Rates in Combined Sexual-Vectorial Transmission Epidemics.Microorganisms · 2019Article
- Global expansion and redistribution of Aedes-borne virus transmission risk with climate change.PLoS neglected tropical diseases · 2019Article
- Prior dengue virus infection and risk of Zika: A pediatric cohort in Nicaragua.PLoS medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zika virus infection was declared a public health emergency of international concern in February 2016 in response to the outbreak in Brazil and its suspected link with congenital anomalies. In this study, we use notification data and disease natural history parameters to estimate the basic reproduction number (R 0) of Zika in Rio de Janeiro, Brazil. We also obtain estimates of R 0 of dengue from time series of dengue cases in the outbreaks registered in 2002 and 2012 in the city, when DENV-3 and DENV-4 serotypes, respectively, had just emerged. Our estimates of the basic reproduction number for Zika in Rio de Janeiro based on surveillance notifications (R 0 = 2·33, 95% CI: 1·97-2·97) were higher than those obtained for dengue in the city (year 2002: R 0 = 1·70 [1·50-2·02]; year 2012: R 0 = 1·25 [1·18-1·36]). Given the role of Aedes aegypti as vector of both the Zika and dengue viruses, we also derive R 0 of Zika as a function of both dengue reproduction number and entomological and epidemiological parameters for dengue and Zika. Using the dengue outbreaks from previous years allowed us to estimate the potential R 0 of Zika. Our estimates were closely in agreement with our first Zika's R 0 estimation from notification data. Hence, these results validate deriving the potential risk of Zika transmission in areas with recurring dengue outbreaks. Whether transmission routes other than vector-based can sustain a Zika epidemic still deserves attention, but our results suggest that the Zika outbreak in Rio de Janeiro emerged due to population susceptibility and ubiquitous presence of Ae. aegypti.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.