Evidence map›Paper›PMID 28238746›Full record

ArticleThe Journal of allergy and clinical immunology2017

Asthma remission: Predicting future airways responsiveness using an miRNA network.

Michael J McGeachie, Joshua S Davis, Alvin T Kho, Amber Dahlin, Joanne E Sordillo, Maoyun Sun, Quan Lu, Scott T Weiss, Kelan G Tantisira

Abstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. The ubiquitin ligase Cul5 regulates CD4Nature communications · 2022
    Article
  5. COPD-associated miR-145-5p is downregulated in early-decline FEVThe Journal of allergy and clinical immunology · 2021
    Article
  6. Molecular networks in Network Medicine: Development and applications.Wiley interdisciplinary reviews. Systems biology and medicine · 2020
    Review
  7. Article
  8. Article
  9. Review
  10. MicroRNAs: Potential Biomarkers and Targets of Therapy in Allergic Diseases?Archivum immunologiae et therapiae experimentalis · 2019
    Review
  11. Reply.The Journal of allergy and clinical immunology · 2019
    Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael J McGeachieChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass. Electronic address: michael.mcgeachie@channing.harvard.edu.
Joshua S DavisChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Alvin T KhoHarvard Medical School, Boston, Mass; Computational Health Informatics Program, Boston Children's Hospital, Boston, Mass.
Amber DahlinChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Joanne E SordilloChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Maoyun SunProgram in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass.
Quan LuProgram in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass.
Scott T WeissChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Kelan G TantisiraChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.

Funding

THE PHARMACOGENETICS OF ASTHMA TREATMENTU01HL065899 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI TANTISIRA, KELAN G, WEISS, SCOTT T · 2000 to 2014
$38.5M
The Genetic Epidemiology of Asthma in Costa RicaR37HL066289 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2007 to 2015
$14.6M
Training Program in Molecular and Integrative Physiological SciencesT32HL007118 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LU, QUAN · 1985 to 2025
$14.3M
SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASEST32HL007427 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI DAWN L DEMEO, Edwin K Silverman · 1985 to 2026
$13.6M
Systems Biology of Airway DiseaseP01HL132825 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2016 to 2020
$12.6M
MICRORNAS IN CIRCULATION: ONTOLOGIES OF ASTHMA SEVERITY AND TREATMENT (MICROCOAST)R01HL127332 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI TANTISIRA, KELAN G · 2015 to 2018
$3.4M
Mechanism and Function of Beta-2 Adrenergic Receptor Degradation in the LungR01HL114769 · NHLBI · HARVARD SCHOOL OF PUBLIC HEALTH · PI LU, QUAN · 2013 to 2016
$1.6M
DISEASE AND HEALTH: ASTHMA RESILIENCE THROUGH MICRORNA ATTRIBUTES (DHARMA)R01HL129935 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI TANTISIRA, KELAN G · 2015 to 2017
$1.4M
GENOMICS AND PHARMACOGENOMICS OF SYMPTOMS IN ASTHMAR01NR013391 · NINR · BRIGHAM AND WOMEN'S HOSPITAL · PI TANTISIRA, KELAN G · 2011 to 2013
$1.3M
Role of microRNA molecules in therapeutic response to leukotriene modifying agents in asthmaK01HL130629 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DAHLIN, AMBER · 2016 to 2020
$818k
An Integrative Genomics Approach to Gene by Environment Interactions in AsthmaR00HL109162 · NHLBI · HARVARD PILGRIM HEALTH CARE, INC. · PI SORDILLO, JOANNE ELAINE · 2014 to 2016
$743k
A Developmental Basis for Chronic Obstructive Lung DiseaseK25HL091124 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI KHO, ALVIN THONG-JUAK · 2008 to 2012
$743k
NHLBI NIH HHS K01 HL130629NHLBI NIH HHS K25 HL091124NHLBI NIH HHS P01 HL132825NHLBI NIH HHS R00 HL109162NHLBI NIH HHS R01 HL114769NHLBI NIH HHS R01 HL127332NHLBI NIH HHS R01 HL129935NHLBI NIH HHS R37 HL066289NHLBI NIH HHS T32 HL007118NHLBI NIH HHS T32 HL007427NHLBI NIH HHS U01 HL065899NINR NIH HHS R01 NR013391
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Area Under CurveAsthmaBronchial HyperreactivityGene Expression RegulationGene Regulatory NetworksGenetic Association StudiesGenetic Predisposition to DiseaseHumansMicroRNAsPhenotypePrognosisMicroRNAs

Identifiers

PMID28238746
PMCPMC5546990

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.