SynthesisThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
A systematic review of East African-Indian family of Mycobacterium tuberculosis in Brazil.
Synthesis in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Mycobacterium tuberculosis complex Lineage 1: A neglected cause of tuberculosis.PLoS neglected tropical diseases · 2025Review
- Genetic Diversity ofPathogens (Basel, Switzerland) · 2024Article
- Article
- The immunogenetics of tuberculosis (TB) susceptibility.Immunogenetics · 2023Review
- Molecular epidemiology of Mycobacterium tuberculosis in Brazil before the whole genome sequencing era: a literature review.Memorias do Instituto Oswaldo Cruz · 2021Review
- Characterization of DNA methylation in MalawianPeerJ · 2020Article
- Genetic diversity ofHeliyon · 2019Article
- Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally.Scientific reports · 2018Article
- Structural Prediction and Mutational Analysis of Rv3906c Gene ofAdvances in bioinformatics · 2018Article
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Authors and funding
10 authors.
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Abstract
introductionThe Mycobacterium tuberculosis East African-Indian (EAI) spoligotyping family (belonging to lineage 1, Indo-Oceanic, defined by the region of deletion RD239) is distributed worldwide, but is more prevalent in Southeast Asia, India, and East Africa. Studies in Latin America have rarely identified EAI. In this study, we describe the occurrence of the EAI family in Brazil.
methodsEAI was identified in a systematic literature review of genetic diversity studies pertaining to M. tuberculosis in Brazil, as well as in a survey conducted in Salvador, Bahia, located in the northeastern region of this country.
resultsThe EAI6-BGD1 spoligotyping family and the EAI5 Spoligotype International Type (SIT) 1983 clade were the most frequently reported, with wide distribution of this particular clade described in Brazil. The distribution of other EAI spoligotyping patterns with broader worldwide distribution was restricted to the southeastern region of the country.
conclusionsEAI may be endemic at a low frequency in Brazil, with some clades indicating increased fitness with respect to this population.
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