ArticleJournal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
Comparison of Associations of DXA and CT Visceral Adipose Tissue Measures With Insulin Resistance, Lipid Levels, and Inflammatory Markers.
Article in Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Body fat and risk of all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies.International journal of obesity (2005) · 2022Pooled it
- Efficacy of ketogenic diet on body composition during resistance training in trained men: a randomized controlled trial.Journal of the International Society of Sports Nutrition · 2018Trial
- Role of systemic and epicardial adipose tissue in cardiometabolic disease.Nature reviews. Cardiology · 2026Review
- Visceral adiposity does not explain increased diabetes rates in Black and Hispanic people in NHANES 2011-2018.Journal of the Endocrine Society · 2026Article
- Visceral Adiposity and Inflammation Index as Predictors of Stroke Risk in Middle and Older Age: A Cohort Study Across Blood Pressure Groups.Brain and behavior · 2025Article
- Clinical Thresholds for Visceral Adiposity Accumulation: A Comparative Analysis in Sex-, Age-, and BMI-Matched Black and White Adults.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- Cross-sectional analysis of visceral adipose tissue associations with obesity-related disease.The American journal of clinical nutrition · 2025Article
- Age-specific and sex-specific associations of visceral adipose tissue with metabolic health status and cardiovascular disease risk.Acta diabetologica · 2025Article
- Monitoring body composition change for intervention studies with advancing 3D optical imaging technology in comparison to dual-energy X-ray absorptiometry.The American journal of clinical nutrition · 2023Article
- Longitudinal Changes in Adiposity and Lower Urinary Tract Symptoms Among Older Men.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Equations for predicting DXA-measured visceral adipose tissue mass based on BMI or weight in adults.Lipids in health and disease · 2022Article
- Official Position of the Brazilian Association of Bone Assessment and Metabolism (ABRASSO) on the evaluation of body composition by densitometry-part II (clinical aspects): interpretation, reporting, and special situations.Advances in rheumatology (London, England) · 2022Article
- Relationships between plasma levels and six proinflammatory interleukins and body composition using a new magnetic resonance imaging voxel-based technique.Cytokine: X · 2021Article
- The association between obesity indices and obstructive sleep apnea is modified by age in a sex-specific manner.Sleep & breathing = Schlaf & Atmung · 2021Article
- Obesity as a Potential Predictor of Disease Severity in Young COVID-19 Patients: A Retrospective Study.Obesity (Silver Spring, Md.) · 2020Article
- Metabolically Healthy, but Obese Individuals and Associations with Echocardiographic Parameters and Inflammatory Biomarkers: Results from the CARLA Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Change in CT-measured abdominal subcutaneous and visceral but not thigh fat areas predict future insulin sensitivity.Diabetes research and clinical practice · 2019Article
- Osteosarcopenic Obesity: Current Knowledge, Revised Identification Criteria and Treatment Principles.Nutrients · 2019Review
- Central Obesity and Visceral Adipose Tissue Are Not Associated With Incident Atherosclerotic Cardiovascular Disease Events in Older Men.Journal of the American Heart Association · 2018Article
- Dose-response effects of exercise on insulin among colon cancer survivors.Endocrine-related cancer · 2018Article
Corrections and comments
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Authors and funding
13 authors at 8 institutions in 1 country.
Funding
Abstract
Visceral adipose tissue (VAT) measured by computed tomography (CT) is related to insulin resistance, lipids, and serum inflammatory markers. Our objective was to compare the strength of the associations of VAT measured using dual-energy X-ray absorptiometry (DXA-VAT) and CT (CT-VAT) with insulin resistance, serum lipids, and serum markers of inflammation. For 1117 men aged 65 and older enrolled in the Osteoporotic Fractures in Men Study, the cross-sectional associations of DXA-VAT and CT-VAT with homeostasis model assessment of insulin resistance (homa2ir), C-reactive protein, and high-density lipoprotein (HDL) cholesterol were estimated with regression models and compared using a Hausman test. Adjusted for age and body mass index, DXA-VAT was moderately associated with homa2ir (effect size 0.38, 95% confidence interval [CI]: 0.28-0.47) and modestly associated with HDL cholesterol (DXA effect size -0.29, 95% CI: -0.38 to -0.21). These associations were significantly greater than those for CT-VAT with homa2ir (0.30, 95% CI: 0.24-0.37; p value for effect size difference 0.03) and CT-VAT with HDL cholesterol (-0.22, 95% CI: -0.29 to -0.15; p value for difference 0.005). Neither DXA-VAT nor CT-VAT was associated with C-reactive protein after adjustment for age and body mass index (DXA-VAT effect size 0.14, 95% CI: -0.04 to 0.32; CT-VAT effect size 0.08, 95% CI: -0.08 to 0.25; p value for difference 0.35). DXA-VAT has similar or greater associations with insulin resistance and HDL cholesterol as does CT-VAT in older men, confirming the concurrent validity of DXA-VAT. Investigations of how well DXA measurements of VAT predict incident cardiovascular disease events are warranted.
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