ArticleJournal of clinical laboratory analysis2018
Delta neutrophil index: A reliable marker to differentiate perforated appendicitis from non-perforated appendicitis in the elderly.
Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 26 citations in OpenAlex.
- Combined delta neutrophil index and red blood cell distribution width as a new biomarker to predict endometriosisJournal of the Turkish German Gynecological Association · 2024Article
- Delta neutrophil index in obese and non-obese polycystic ovary syndrome patients.Obstetrics & gynecology science · 2023Article
- Review
- The role of immature granulocyte in the early prediction of acute perforated and nonperforated appendicitis in children.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Complicated or non-complicated appendicitis? That is the question.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Acute Appendicitis in the Elderly: A Literature Review on an Increasingly Frequent Surgical Problem.Geriatrics (Basel, Switzerland) · 2021Review
- Predictive Efficacy of Delta Neutrophil Index in Diagnosis of Acute and Complicated Appendicitis.Cureus · 2021Article
- Delta Neutrophil Index for the Prediction of Prognosis in Acute Gastrointestinal Diseases; Diagnostic Test Accuracy Meta-Analysis.Journal of clinical medicine · 2020Article
- Delta neutrophil index as a prognostic marker in emergent abdominal surgery.Journal of clinical laboratory analysis · 2019Article
- Delta neutrophil index: A reliable marker to differentiate perforated appendicitis from non-perforated appendicitis in the elderly.Journal of clinical laboratory analysis · 2018Article
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDelta neutrophil index (DNI) is a new inflammatory marker and the present study aimed to evaluate the predictive value of the DNI for the presence of a perforation in elderly with acute appendicitis.
methodsThis retrospective observational study was conducted on 108 consecutive elderly patients (≥65 years old) with acute appendicitis treated over a 24-month period.
resultsSixty-nine of the 108 patients (median, IQR: 72, 67-77 years) were allocated to the perforated appendicitis group (63.9%) and 39 to the non-perforated appendicitis group (36.1%). WBC, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and DNI were significantly higher in the perforated group. In multiple logistic regression analyses, initial DNI was the only independent marker that can significantly predict the presence of perforation in multiple regression [odds ratio 9.38, 95% confidence interval (2.51-35.00), P=.001]. Receiver operator characteristic curve analysis showed that DNI is a good predictor for the presence of appendiceal perforation at an optimal cut-off for DNI being 1.4% (sensitivity 67.7%, specificity 90.0%, AUC 0.807).
conclusionClinicians can reliably differentiate acute perforated appendicitis from non-perforated appendicitis by DNI level of 1.4 or more in elderly patients.
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