Evidence map›Paper›PMID 28238163›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2017

Use of rivaroxaban in patients with stroke.

Danilo Toni, Antonio Carolei, Valeria Caso, Domenico Consoli, Massimo Del Sette, Domenico Inzitari, Maurizio Melis, Giuseppe Micieli, Leandro Provinciali, Stefano Ricci and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Danilo ToniUnità di Trattamento Neurovascolare, University La Sapienza Rome, Viale del Policlinico 155, 00161, Rome, Italy. danilo.toni@uniroma1.it.
Antonio CaroleiDepartment of Applied Clinical Sciences and Biotechnology, University of L'Aquila, L'Aquila, Italy.
Valeria CasoStroke Unit, Perugia, Italy.
Domenico ConsoliU.O. Neurologia e Stroke Unit, PO "G. Jazzolino", Vibo Valentia, VV, Italy.
Massimo Del SetteS.C. Neurologia, Ente Ospedaliero Ospedali Galliera Genova, Genoa, Italy.
Domenico InzitariDepartment of NEUROFARBA, Neuroscience SectionUniversity of Florence, Florence, Italy.
Maurizio MelisSC Neurologia e Stroke UnitAzienda Ospedaliera G. Brotzu, Cagliari, Italy.
Giuseppe MicieliDipartimento di Neurologia d'Urgenza, IRCCS Fondazione Istituto Neurologico Nazionale C. Mondino, Pavia, Italy.
Leandro ProvincialiClinica Neurologica, Università Politecnica delle Marche, Ancona, Italy.
Stefano RicciUO Neurologia, USL Umbria 1, Sedi di Città di Castello e Branca, Trento, Italy.
Paola SantaluciaFondazione IRCCS Ospedale Maggiore Policlinico, Milan, Italy.
Vito TosoItalian Stroke Organisation, Florence, Italy.
Azienda Ospedaliera G. Brotzu · ITCittà di Castello Hospital · ITEnte Ospedaliero Ospedali Galliera · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITFondazione Istituto Neurologico Nazionale Casimiro Mondino · ITMarche Polytechnic University · ITUniversity of Florence · ITUniversity of L'Aquila · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rivaroxaban, an inhibitor of Factor Xa, is a direct oral anti-coagulant that has been found to be non-inferior to warfarin in preventing cerebral ischemia in patients with non-valvular atrial fibrillation and in the subgroup of patients with a history of the previous stroke or transient ischemic attack. Vascular neurologists in daily clinical practice may encounter patients taking rivaroxaban or patients who may benefit from its use. In this paper, we review the current clinical indications, contraindications, and clinical management guidelines for rivaroxaban while providing a special focus on neurological aspects and expert opinions on rivaroxaban therapy management in various situations that a neurologist may encounter when treating patients with an ischemic stroke (including those requiring intravenous or intra-arterial reperfusion therapy) and patients with an intracerebral hemorrhage. Since data from clinical trials and real-life data are missing in some clinical situations, strong recommendations are not always available. Nevertheless, practical guidelines should be adopted to maximize benefits from this oral anti-coagulant.

Indexed as

Factor Xa InhibitorsHumansRivaroxabanStrokeFactor Xa InhibitorsRivaroxabanAnti-coagulantsAtrial fibrillationIntracerebral hemorrhageIschemic strokeRivaroxaban

Identifiers

PMID28238163
OpenAlexW2590095782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.