Evidence map›Paper›PMID 28238109›Full record

ArticleEuropean journal of nutrition2018

Erythrocyte fatty acid composition of Nepal breast-fed infants.

Sigrun Henjum, Øyvind Lie, Manjeswori Ulak, Andrew L Thorne-Lyman, Ram K Chandyo, Prakash S Shrestha, Wafaie W Fawzi, Tor A Strand, Marian Kjellevold

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03668977 (Impact of a Balanced Protein-Energy Supplement in Pregnancy and Early Lactation on Reproductive Outcomes and Growth in Southern Nepal), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03668977 nacompletednot on this map

Impact of a Balanced Protein-Energy Supplement in Pregnancy and Early Lactation on Reproductive Outcomes and Growth in Southern Nepal

TypeinterventionalSponsorGeorge Washington UniversityRan2018 to 2024Enrolled1,944ConditionsPregnancy and Early Lactation Among Women Living in an Area Endemic for MalnutritionArmsFortified balanced protein-energy.
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Sigrun HenjumOslo and Akershus University College of Applied Sciences, St. Olavs plass, P.O. Box 4, 0130, Oslo, Norway. sigrun.henjum@hioa.no.
Øyvind LieNational Institute of Nutrition and Seafood Research (NIFES), P.O. Box 2029, 5817, Bergen, Norway.
Manjeswori UlakDepartment of Child Health, Institute of Medicine, Tribhuvan University, Maharajgunj, P.O. Box 1524, 44600, Kathmandu, Nepal.
Andrew L Thorne-LymanCenter for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.
Ram K ChandyoDepartment of Community Medicine, Kathmandu Medical College, 21266, Kathmandu, Nepal.
Prakash S ShresthaDepartment of Child Health, Institute of Medicine, Tribhuvan University, Maharajgunj, P.O. Box 1524, 44600, Kathmandu, Nepal.
Wafaie W FawziDepartments of Nutrition, Epidemiology, and Global Health and Population, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA, 02115, USA.
Tor A StrandDepartment of Research, Innlandet Hospital Trust and Centre for International Health, University of Bergen, 2629, Lillehammer, Norway.
Marian KjellevoldNational Institute of Nutrition and Seafood Research (NIFES), P.O. Box 2029, 5817, Bergen, Norway.
Tribhuvan University Teaching Hospital · NPInnlandet Hospital Trust · NOJohns Hopkins University · USKathmandu Medical College Teaching Hospital · NPOsloMet – Oslo Metropolitan University · NO

Funding

Norges Forskningsråd (NO)172226 172226South-Eastern Norway Regional Health Authority 2012090
6 · The paper itself

Abstract

purposeEssential fatty acids play a critical role in the growth and development of infants, but little is known about the fatty acid status of populations in low-income countries. The objective was to describe the fatty acid composition of red blood cells (RBC) in breastfeed Nepali infants and a subsample of their mothers and to identify the main sources of fatty acids in the mother's diet, as well as the fatty acid composition of breast milk.

methodsRBC fatty acid composition was analyzed in a random sample of 303 infants and 72 mother, along with 68 breastmilk samples. Fatty acid profiles of the most important dietary fat sources were analyzed. Information on mother's diet and intake of fat was collected by three 24-h dietary recalls.

resultsIn infant RBC's, docosahexaenoic acid (DHA) was the main n-3 fatty acid, and arachidonic acid (AA) was the major n-6 fatty acid. Total n-6 PUFA was three times higher than total n-3 PUFA. Height-for-age (HAZ) was positively associated with DHA status and AA status in multivariable models. The concentration of all fatty acids was higher in children, compared to mothers, except Total n-6 PUFA and Linoleic acid (LA) where no differences were found. The mother's energy intake from fat was 13% and cooking oil (sesame, mustard, soybean or sunflower oil) contributed 52% of the fat intake.

conclusionsRBC-DHA levels in both infants and mother was unexpected high taking into account few dietary DHA sources and the low DHA concentrations in breastmilk.

Indexed as

Breast FeedingMaternal Nutritional Physiological PhenomenaAdultChild DevelopmentCross-Sectional StudiesDeficiency DiseasesDiet, Fat-RestrictedErythrocytesFatty AcidsFatty Acids, EssentialFemaleGrowth DisordersHumansInfantMaleMilk, HumanFatty AcidsFatty Acids, EssentialPlant OilsAABreast-fed childrenBreastmilkDHAPlasma phospholipidsPolyunsaturated fatty acids

Identifiers

PMID28238109
OpenAlexW2590710493

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.