Evidence map›Paper›PMID 28238048›Full record

ArticleEuropean journal of applied physiology2017

Dynamics of the RR-interval versus blood pressure relationship at exercise onset in humans.

Aurélien Bringard, Alessandra Adami, Nazzareno Fagoni, Timothée Fontolliet, Frédéric Lador, Christian Moia, Enrico Tam, Guido Ferretti

Abstract read
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Article in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aurélien BringardDépartement d'Anesthésiologie, Pharmacologie et Soins Intensifs, Hôpitaux Universitaires de Genève, 4 rue Gabrielle-Perret-Gentil, CH-1211, Genève 4, Switzerland.
Alessandra AdamiDépartement des Neurosciences Fondamentales, Université de Genève, 1 rue Michel Servet, CH-1211, Genève 4, Switzerland.
Nazzareno FagoniDipartimento di Medicina Molecolare e Traslazionale, Università di Brescia, Viale Europa 11, 25123, Brescia, Italy.
Timothée FontollietDépartement d'Anesthésiologie, Pharmacologie et Soins Intensifs, Hôpitaux Universitaires de Genève, 4 rue Gabrielle-Perret-Gentil, CH-1211, Genève 4, Switzerland.
Frédéric LadorService de Pneumologie, Programme Hypertension Pulmonaire, Département des Spécialités de Médecine, Hôpitaux Universitaires de Genève, 4 rue Gabrielle-Perret-Gentil, CH-1211, Genève, Switzerland.
Christian MoiaDépartement d'Anesthésiologie, Pharmacologie et Soins Intensifs, Hôpitaux Universitaires de Genève, 4 rue Gabrielle-Perret-Gentil, CH-1211, Genève 4, Switzerland.
Enrico TamDipartimento di Scienze Neurologiche, Biomediche e del Movimento, Università di Verona, Via Felice Casorati 43, 37131, Verona, Italy.
Guido FerrettiDépartement d'Anesthésiologie, Pharmacologie et Soins Intensifs, Hôpitaux Universitaires de Genève, 4 rue Gabrielle-Perret-Gentil, CH-1211, Genève 4, Switzerland. Guido.Ferretti@unige.ch.ORCID http://orcid.org/0000-0001-7592-0416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe dynamics of the postulated phenomenon of exercise baroreflex resetting is poorly understood, but can be investigated using closed-loop procedures. To shed light on some mechanisms and temporal relationships participating in the resetting process, we studied the time course of the relationship between the R-R interval (RRi) and arterial pressure with a closed-loop approach.

methodsOn ten young volunteers at rest and during light exercise in supine and upright position, we continuously determined, on single-beat basis, RRi (electrocardiography), and arterial pressure (non-invasive finger pressure cuff). From pulse pressure profiles, we determined cardiac output (CO) by Modelflow, computed mean arterial pressure (MAP), and calculated total peripheral resistance (TPR).

resultsAt exercise start, RRi was lower than in quiet rest. As exercise started, MAP fell to a minimum (MAP

conclusionThese results suggest that, initially, the MAP fall was corrected by a RRi reduction along a baroreflex curve, with lower sensitivity than at rest, but eventually in the same pressure range as at rest. After attainment of MAP

Indexed as

BaroreflexBlood PressureAdultCardiac OutputExerciseFemaleHumansMalePostureBaroreflex resettingBaroreflex sensitivityExercise transientsHeart rateMean arterial pressurePeripheral resistance

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.