Evidence map›Paper›PMID 28237603›Full record

ArticleAquatic toxicology (Amsterdam, Netherlands)2017

Embryonic-only arsenic exposure in killifish (Fundulus heteroclitus) reduces growth and alters muscle IGF levels one year later.

Dana B Szymkowicz, Kaleigh C Sims, Noemi M Castro, William C Bridges, Lisa J Bain

Abstract read
In one paragraph

Article in Aquatic toxicology (Amsterdam, Netherlands), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dana B SzymkowiczEnvironmental Toxicology Graduate Program, Clemson University, Clemson, SC, United States.
Kaleigh C SimsEnvironmental Toxicology Graduate Program, Clemson University, Clemson, SC, United States.
Noemi M CastroDepartment of Biochemistry and Molecular Biology, University of California-Davis, Davis, CA, United States.
William C BridgesDepartment of Mathematical Sciences, Clemson University, Clemson, SC, United States.
Lisa J BainEnvironmental Toxicology Graduate Program, Clemson University, Clemson, SC, United States; Department of Biological Sciences, Clemson University, Clemson, SC, United States. Electronic address: lbain@clemson.edu.
Clemson University · USUniversity of California, Davis · US

Funding

Embryonic Arsenic Exposure Impacts Satellite CellsR03ES023930 · NIEHS · CLEMSON UNIVERSITY · PI BAIN, LISA J · 2015 to 2016
$142k
NIEHS NIH HHS R03 ES023930
6 · The paper itself

Abstract

Arsenic is a contaminant of drinking water and crops in many parts of the world. Epidemiological studies have shown that arsenic exposure is linked to decreased birth weight, weight gain, and proper skeletal muscle function. The goal of this study was to use killifish (Fundulus heteroclitus) as a model to determine the long-term effects of embryonic-only arsenic exposure on muscle growth and the insulin-like growth factor (IGF) pathway. Killifish embryos were exposed to 0, 50, 200 or 800ppb As

Indexed as

AnimalsArsenicBehavior, AnimalEmbryonic DevelopmentEnvironmental ExposureFemaleFundulidaeGene Expression Regulation, DevelopmentalInsulin-Like Growth Factor IMuscle Fibers, SkeletalMuscle, SkeletalPregnancyPrenatal Exposure Delayed EffectsReceptor, IGF Type 1RNA, MessengerWater Pollutants, ChemicalArsenicInsulin-Like Growth Factor IReceptor, IGF Type 1RNA, MessengerWater Pollutants, ChemicalArsenicEmbryoIGF-1IGF-1RKillifishSkeletal muscle

Identifiers

PMID28237603
PMCPMC5395342
OpenAlexW2591221082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.