Evidence map›Paper›PMID 28237048›Full record

Trial reportJournal of substance abuse treatment2017

Heterogeneity in pathways to abstinence among women in treatment for alcohol use disorder.

Cathryn Glanton Holzhauer, Elizabeth E Epstein, Amy M Cohn, Barbara S McCrady, Fiona S Graff, Sharon Cook

Erratum issuedOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of substance abuse treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Cathryn Glanton HolzhauerDepartment of Psychiatry, University of Massachusetts Medical School, USA. Electronic address: cathryn.holzhauer@umassmed.edu.
Elizabeth E EpsteinDepartment of Psychiatry, University of Massachusetts Medical School, USA; Center of Alcohol Studies, Rutgers University, USA.
Amy M CohnSchroeder Institute for Tobacco Research and Policy Studies at Truth Initiative, USA; Department of Oncology, Georgetown University Medical Center, Cancer Prevention and Control Program, USA.
Barbara S McCradyCenter of Alcohol Studies, Rutgers University, USA; Center on Alcoholism, Substance Abuse, and Addictions, University of New Mexico, USA.
Fiona S GraffWar-Related Illness and Injury Study Center, VA NJ Health Care System, USA.
Sharon CookCenter of Alcohol Studies, Rutgers University, USA.
University of Massachusetts Chan Medical School · USAlcohol Research Group · USGeorgetown University Medical Center · USRutgers, The State University of New Jersey · USVA New Jersey Health Care System · US

Funding

TESTING ALCOHOL BEHAVIORAL COUPLES THERAPY FOR WOMENR37AA007070 · NIAAA · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI MCCRADY, BARBARA S · 1998 to 2006
$3.6M
TESTING ALCOHOL BEHAVIORAL COUPLES THERAPY FOR WOMENR01AA007070 · NIAAA · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI EPSTEIN, ELIZABETH E · 1988 to 2007
$596k
NIAAA NIH HHS L30 AA025236NIAAA NIH HHS R01 AA007070NIAAA NIH HHS R37 AA007070
6 · The paper itself

Abstract

backgroundAlthough many providers recommend alcohol abstinence as an initial step in the treatment of alcohol use disorders (AUD), there is a scarcity of research on specific behavioral strategies to achieve this step. The current study examined efficacy of a unique abstinence planning intervention for alcohol in a cognitive behavioral therapy (CBT) outpatient protocol.

design128 women enrolled in a randomized controlled trial of CBT for AUD at a university-based clinic comprised the sample. MEASUREMENTS: Session 1 manual-guided interventions included an abstinence planning discussion in which each woman chose a specific plan for achieving initial abstinence in collaboration with her therapist. Drinking data were collected via participant logs during the 16week within-treatment period and via Timeline Follow-Back interview at 12month follow-up.

findingsFor 32.8% (n=42) of women who stopped drinking during the pre-treatment assessment period, their abstinence plan was to maintain abstinence (MA). 18.0% (n=23) of women chose a "cold turkey" approach (CT, abrupt cessation without medical assistance), and 46.1% (n=59) chose a "winding down" approach (WD, systematic reduction of drinking toward a specified quit date). Generalized Estimating Equations (GEE) analyses showed that type of abstinence plan chosen was differentially associated with percent days drinking (PDD) in later treatment (weeks 7-16) (p<0.01) and during 12month follow-up (p<0.01). Women in the WD group had the highest PDD for both time frames and women in the CT group drank more frequently during later treatment compared to those in the MA group. The association between plan and PDD during follow-up was moderated by early treatment PDD (weeks 1-7; p<0.01), such that women in the MA and WD groups had lower follow-up PDD if they were able to decrease their drinking during early treatment.

conclusionsWomen who were maintaining abstinence at treatment entry or had planned to stop using alcohol abruptly (i.e., "cold turkey") after starting treatment had better overall drinking outcomes than those who chose to wind down. A plan to wind-down drinking appeared to be the most appealing option to women in the study and, among those who were able to successfully execute this winding down approach, was related to positive long-term drinking outcomes.

Indexed as

Alcohol AbstinenceAlcoholismAmbulatory CareCognitive Behavioral TherapyFemaleHumansMiddle AgedTreatment OutcomeWomen's HealthAbstinenceAlcoholTreatmentTreatment PlanningWomen

Identifiers

PMID28237048
PMCPMC5329902
OpenAlexW2574940986

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.