Evidence map›Paper›PMID 28236761›Full record

ArticleBrain and language2017

Activity associated with speech articulation measured through direct cortical recordings.

Alexandra Basilakos, Julius Fridriksson, Chris Rorden, Roozbeh Behroozmand, Taylor Hanayik, Thomas Naselaris, John Del Gaizo, Jesse Breedlove, W A Vandergrift, Leonardo Bonilha

Abstract read
In one paragraph

Article in Brain and language, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. High-level language brain regions process sublexical regularities.Cerebral cortex (New York, N.Y. : 1991) · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexandra BasilakosDepartment of Communication Sciences and Disorders, University of South Carolina, Columbia, SC 29208, United States.
Julius FridrikssonDepartment of Communication Sciences and Disorders, University of South Carolina, Columbia, SC 29208, United States.
Chris RordenDepartment of Psychology, University of South Carolina, Columbia, SC 29208, United States.
Roozbeh BehroozmandDepartment of Communication Sciences and Disorders, University of South Carolina, Columbia, SC 29208, United States.
Taylor HanayikDepartment of Psychology, University of South Carolina, Columbia, SC 29208, United States.
Thomas NaselarisDepartment of Neurology, Medical University of South Carolina, Charleston, SC 29425, United States.
John Del GaizoDepartment of Neurology, Medical University of South Carolina, Charleston, SC 29425, United States.
Jesse BreedloveDepartment of Neurology, Medical University of South Carolina, Charleston, SC 29425, United States.
W A VandergriftDepartment of Neurosurgery, Medical University of South Carolina, Charleston, SC 29425, United States.
Leonardo BonilhaDepartment of Neurology, Medical University of South Carolina, Charleston, SC 29425, United States. Electronic address: bonilha@musc.edu.

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HICKOK, GREGORY · 2016 to 2025
$25.0M
Cortical and Subcortical Organization of Language-Related Semantic Processing in Alzheimer's DiseaseR01DC014021 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BONILHA, LEONARDO F · 2014 to 2023
$4.7M
A Unified Neuroanatomical Model of Speech Production and Perception: ImplicationsR01DC009571 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FRIDRIKSSON, JULIUS, RORDEN, CHRISTOPHER · 2009 to 2013
$1.6M
NIDCD NIH HHS P50 DC014664NIDCD NIH HHS R01 DC009571NIDCD NIH HHS R01 DC014021
6 · The paper itself

Abstract

The insula has been credited with a role in a number of functions, including speech production. Here, we recorded electrocorticography (ECoG) signals from the left insula during pseudoword articulation in two patients undergoing pre-surgical monitoring for the management of medically-intractable epilepsy. Event-related band power (ERBP) activity from electrodes implanted in the superior precentral gyrus of the insula (SPGI) was compared to that of other left hemisphere regions implicated in speech production. Results showed that SPGI contacts demonstrated significantly greater ERBP within the high-gamma frequency range (75-150Hz) during articulation compared to a listening condition. However, frontal and post-central regions demonstrated significantly greater responses to the articulation task compared to the SPGI. Results suggest the SPGI is active during articulation, but frontal and post-central regions demonstrate significantly more robust responses. Given the small sample size, and number of electrodes implanted in the SPGI, further study is warranted to confirm these findings.

Indexed as

Brain MappingAdultAuditory PerceptionCerebral CortexElectrodes, ImplantedElectroencephalographyEpilepsyFemaleHumansSample SizeSpeechArticulationElectrocorticographyInsulaSpeech production

Identifiers

PMID28236761
PMCPMC5417075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.