Evidence map›Paper›PMID 28236714›Full record

ArticlePsychiatry research. Neuroimaging2017

Neural correlates of graphic cigarette warning labels predict smoking cessation relapse.

Max M Owens, James MacKillop, Joshua C Gray, Brittany E Hawkshead, Cara M Murphy, Lawrence H Sweet

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychiatry research. Neuroimaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Social networks and neural receptivity to persuasive health messages.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021
    Article
  5. Article
  6. Article
  7. Striato-cortical tracts predict 12-h abstinence-induced lapse in smokers.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018
    Article
  8. Associations between coherent neural activity in the brain's value system during antismoking messages and reductions in smoking.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018
    Article
  9. Neurophysiological Profile of Antismoking Campaigns.Computational intelligence and neuroscience · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Max M OwensDepartment of Psychology, The University of Georgia, Athens, GA, USA. Electronic address: owensmax@uga.edu.
James MacKillopDepartment of Psychology, The University of Georgia, Athens, GA, USA; Peter Boris Centre for Addictions Research and Department of Psychiatry and Behavioural Neurosciences, McMaster University/St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada; Department of Psychiatry, Brown University, Providence, RI, USA.
Joshua C GrayDepartment of Psychology, The University of Georgia, Athens, GA, USA; Department of Psychiatry, Brown University, Providence, RI, USA.
Brittany E HawksheadDepartment of Psychology, The University of Georgia, Athens, GA, USA.
Cara M MurphyPeter Boris Centre for Addictions Research and Department of Psychiatry and Behavioural Neurosciences, McMaster University/St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
Lawrence H SweetDepartment of Psychology, The University of Georgia, Athens, GA, USA; Department of Psychiatry, Brown University, Providence, RI, USA.

Funding

Enhancing Alcoholism Pharmacotherapy Research via Behavioral EconomicsK23AA016936 · NIAAA · UNIVERSITY OF GEORGIA · PI MACKILLOP, JAMES · 2008 to 2012
$805k
Neuroimaging approaches to improve prediction of relapse during smoking cessationR21DA031269 · NIDA · UNIVERSITY OF GEORGIA · PI SWEET, LAWRENCE H · 2012 to 2013
$384k
NIAAA NIH HHS K23 AA016936NIDA NIH HHS R21 DA031269
6 · The paper itself

Abstract

Exposure to graphic warning labels (GWLs) on cigarette packaging has been found to produce heightened activity in brain regions central to emotional processing and higher-order cognitive processes. The current study extends this literature by using functional magnetic resonance imaging (fMRI) to investigate neural activation in response to GWLs and use it to predict relapse in an evidence-based smoking cessation treatment program. Participants were 48 treatment-seeking nicotine-dependent smokers who completed an fMRI paradigm in which they were exposed to GWLs, text-only warning labels (TOLs), and matched control stimuli. Subsequently, they enrolled in smoking cessation treatment and their smoking behavior was monitored. Activation in bilateral amygdala, right dorsolateral prefrontal cortex, right inferior frontal gyrus, left medial temporal gyrus, bilateral occipital lobe, and bilateral fusiform gyrus was greater during GWLs than TOLs. Neural response in the ventromedial prefrontal cortex (vmPFC) during exposure to GWLs (relative to a visual control image) predicted relapse during treatment beyond baseline demographic and dependence severity, but response in the amygdala to GWLs did not. These findings suggest that neurocognitive processes in the vmPFC may be critical to understanding how GWL's induce behavior change and may be useful as a predictor of smoking cessation treatment prognosis.

Indexed as

Product LabelingAdultBrainEmotionsFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPrognosisRecurrenceSmokingSmoking CessationFunctional magnetic resonance imagingMedial prefrontal cortexNicotine dependenceRelapseSmoking cessationWarning labels

Identifiers

PMID28236714
PMCPMC5404379

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.