Evidence map›Paper›PMID 28236480›Full record

ArticleThe Science of the total environment2017

Effect of biodiesel fuel on "real-world", nonroad heavy duty diesel engine particulate matter emissions, composition and cytotoxicity.

Nathan Martin, Melissa Lombard, Kirk R Jensen, Patrick Kelley, Tara Pratt, Nora Traviss

Abstract read
In one paragraph

Article in The Science of the total environment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Effects of fuel components and combustion particle physicochemical properties on toxicological responses of lung cells.Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nathan MartinDepartment of Environmental Studies, Keene State College, Keene, NH, 03431, United States.
Melissa LombardDepartment of Earth Sciences, University of New Hampshire, Durham, NH 03824, United States.
Kirk R JensenDepartment of Chemistry and Geochemistry, Colorado School of Mines, Golden, CO, 80401, United States.
Patrick KelleyDepartment of Environmental Studies, Keene State College, Keene, NH, 03431, United States.
Tara PrattDepartment of Environmental Studies, Keene State College, Keene, NH, 03431, United States.
Nora TravissDepartment of Environmental Studies, Keene State College, Keene, NH, 03431, United States. Electronic address: ntraviss@keene.edu.

Funding

Ultrastructural analysis of axonal Kv2-mediated endoplasmic reticulum/plasma membrane (ER/PM) junctionsP20GM103506 · NIGMS · DARTMOUTH COLLEGE · PI STEVEN FIERING · 2012 to 2026
$60.1M
Real world biodiesel particulate matter exposure and toxicological responsesR15ES022431 · NIEHS · KEENE STATE COLLEGE · PI TRAVISS, NORA · 2013 to 2013
$416k
NIEHS NIH HHS R15 ES022431NIGMS NIH HHS P20 GM103506
6 · The paper itself

Abstract

Biodiesel is regarded by many as a "greener" alternative fuel to petroleum diesel with potentially lower health risk. However, recent studies examining biodiesel particulate matter (PM) characteristics and health effects are contradictive, and typically utilize PM generated by passenger car engines in laboratory settings. There is a critical need to analyze diesel and biodiesel PM generated in a "real-world" setting where heavy duty-diesel (HDD) engines and commercially purchased fuel are utilized. This study compares the mass concentrations, chemical composition and cytotoxicity of real-world PM from combustion of both petroleum diesel and a waste grease 20% biodiesel blend (B20) at a community recycling center operating HDD nonroad equipment. PM was analyzed for metals, elemental/organic carbon (EC/OC), polycyclic aromatic hydrocarbons (PAHs), and nitro-polycyclic aromatic hydrocarbons (N-PAHs). Cytotoxicity in a human lung epithelial cell line (BEAS-2B) following 24h exposure to the real-world particles was also evaluated. On average, higher concentrations for both EC and OC were measured in diesel PM. B20 PM contained significantly higher levels of Cu and Mo whereas diesel PM contained significantly higher concentrations of Pb. Principal component analysis determined Mo, Cu, and Ni were the metals with the greatest loading factor, suggesting a unique pattern related to the B20 fuel source. Total PAH concentration during diesel fuel use was 1.9 times higher than during B20 operations; however, total N-PAH concentration was 3.3 times higher during B20 use. Diesel PM cytotoxicity was 8.5 times higher than B20 PM (p<0.05) in a BEAS-2B cell line. This study contributes novel data on real-world, nonroad engine sources of metals, PAH and N-PAH species, comparing tailpipe PM vs. PM collected inside the equipment cabin. Results suggest PM generated from burning petroleum diesel in nonroad engines may be more harmful to human health, but the links between exposure, composition and toxicity are not straightforward.

Indexed as

BiofuelsAir PollutantsCell LineEpithelial CellsGasolineHumansParticulate MatterPolycyclic Aromatic HydrocarbonsVehicle EmissionsAir PollutantsBiofuelsGasolineParticulate MatterPolycyclic Aromatic HydrocarbonsVehicle EmissionsBiodieselCytotoxicityMetalsN-PAHsPAHsParticulate matter

Identifiers

PMID28236480
PMCPMC7372720

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.