ArticleInfection2017
Group B streptococcal disease in infants in the first year of life: a nationwide surveillance study in Japan, 2011-2015.
Article in Infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Clinical Risk Factors Associated With Late-Onset Invasive Group B Streptococcal Disease: Systematic Review and Meta-Analyses.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Pooled it
- Article
- Economic evaluation of prenatal GBS immunization in China: A modeling analysis.Human vaccines & immunotherapeutics · 2025Article
- Neonatal Group B Streptococcus Disease.Pediatrics in review · 2024Review
- Cost-effectiveness analysis of maternal vaccination against Group B streptococcus in Japan.Vaccine: X · 2023Article
- Neonatal Late-Onset Meningitis Caused by Serotype III CC17 Group BInfection and drug resistance · 2023Article
- Epidemiology and bacterial characteristics of invasive group B streptococcus disease: a population-based study in Japan in 2010-2020.Epidemiology and infection · 2022Article
- Epidemiology of group B streptococcal disease in infants younger than 1 year in Japan: a nationwide surveillance study 2016-2020.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022Article
- Newborn Septic Arthritis-A Rare Presentation of Late-Onset Group B Streptococcal Disease: Case Report and Short Review of the Literature.AJP reports · 2021Article
- National database study of trends in bacteraemia aetiology among children and adults in Japan: a longitudinal observational study.BMJ open · 2021Observational
- Group B Streptococcus Screening Guidelines in Pregnancy: A Critical Review of Compliance.Maternal and child health journal · 2021Review
- Understanding Factors in Group B Streptococcus Late-Onset Disease.Infection and drug resistance · 2021Review
- Invasive Group B Streptococcus Disease With Recurrence and in Multiples: Towards a Better Understanding of GBS Late-Onset Sepsis.Frontiers in immunology · 2021Article
- Article
- Clinical and Microbiological Characteristics of Group B Streptococcus from Pregnant Women and Diseased Infants in Intrapartum Antibiotic Prophylaxis Era in Taiwan.Scientific reports · 2019Article
- Group BMicrobiology spectrum · 2019Review
- Changes in the incidence and epidemiology of neonatal group B Streptococcal disease over the last two decades in Crete, Greece.Infectious disease reports · 2018Article
- Difficulties in establishing the source of infection in recurrent neonatal group B streptococcal disease.Infection · 2018Article
- Management of group b streptococcus-positive pregnant women at maternity homes in JAPAN: a questionnaire survey of compliance among midwives.Maternal health, neonatology and perinatology · 2018Article
- Current status of group BZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsArticle
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Authors and funding
8 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to describe the epidemiology of childhood group B streptococcus (GBS) disease including late late-onset disease (LLOD) and to clinically characterize recurrent cases and twin-sibling cases in Japan.
methodsWe collected information on infants (<1 year of age) with invasive GBS disease and institutional information about births and transfers through a nationwide questionnaire between 2011 and 2015.
resultsWe identified 133 infants with early-onset disease (EOD), 274 late-onset disease (LOD), and 38 LLOD from 149 institutes. The case fatality rate (CFR) of EOD, LOD, and LLOD was 4.5, 4.4, and 0%, respectively. CFR in EOD was significantly (P < 0.001) associated with preterm birth, but not that in LOD and LLOD. Twenty-nine percent of infants with meningitis (49/169) had neurologic sequelae. We showed clinical details of 12 recurrent cases that accounted for 2.8% of the total patients, and 4 sets of both twins affected; 4 of 12 recurrent cases and 3 of 4 twin-sibling sets were also associated with preterm birth. Based on the livebirth number of 581,488, the instituted-based incidence of EOD, LOD, and LLOD was estimated as 0.09 (95% CI 0.06-0.11), 0.12 (95% CI 0.11-0.14), and 0.01 (95% CI 0.01-0.02) per 1000 livebirths, respectively.
conclusionsCFR of EOD and LOD in Japan is comparable with that in high-income European countries or the United States, and their incidence is much lower. Our findings also describe the clinical details of LLOD, recurrent infections, and infections in twin siblings. This study is the largest among Asian childhood GBS studies ever reported.
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