ArticleClinical research in cardiology : official journal of the German Cardiac Society2017
Impact of multi-vessel versus single-vessel disease on outcomes after percutaneous coronary interventions for chronic total occlusions.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Outcomes of isolated ostial LAD PCI versus multivessel PCI including ostial LAD lesions.American heart journal plus : cardiology research and practice · 2026Article
- Residual glucose metabolism and Long-Term clinical outcomes in multivessel coronary artery disease: A cohort study.Endocrine · 2026Article
- A Systematic Review of risk factors for major adverse cardiovascular events in patients with coronary heart disease who underwent percutaneous coronary intervention.Frontiers in physiology · 2025Article
- Comparative Ten-Year Outcomes in Chronic and Acute Coronary Syndrome Patients Undergoing Invasive Diagnostics-Insights from the KORONEF Registry.Biomedicines · 2024Article
- Predictive factors for multivessel disease in patients with acute coronary syndrome: analysis from the CCC-ACS project in China.BMC cardiovascular disorders · 2024Article
- The relative and combined ability of triglyceride-glucose index and stress hyperglycemia ratio to predict major adverse cardio-cerebral events in patients with multivessel coronary artery disease.Diabetology & metabolic syndrome · 2024Article
- Review
- Comprehensive analysis of the association between triglyceride-glucose index and coronary artery disease severity across different glucose metabolism states: a large-scale cross-sectional study from an Asian cohort.Cardiovascular diabetology · 2024Article
- High stress hyperglycemia ratio predicts adverse clinical outcome in patients with coronary three-vessel disease: a large-scale cohort study.Cardiovascular diabetology · 2024Observational
- Association between glycemia and multi-vessel lesion in participants undergoing coronary angiography: a cross-sectional study.Frontiers in cardiovascular medicine · 2024Article
- Current Guideline Risk Stratification and Cardiovascular Outcomes in Chinese Patients Suffered From Atherosclerotic Cardiovascular Disease.Frontiers in endocrinology · 2022Article
- Chronic total occlusion percutaneous coronary intervention in everyday clinical practice - an expert opinion of the Association of Cardiovascular Interventions of the Polish Cardiac Society.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2021Review
- Article
- Article
- Successful revascularization of right coronary artery chronic total occlusion by the antegrade and retrograde approaches.AME case reports · 2019Article
- Temporal changes in outcomes of women and men undergoing percutaneous coronary intervention for chronic total occlusion: 2005-2013.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Article
- Outcomes of patients with periprocedural atrial fibrillation undergoing percutaneous coronary intervention for chronic total occlusion.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Review
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Authors and funding
9 authors.
Funding
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Abstract
backgroundSuccessful chronic total occlusion (CTO) revascularization has been associated with prognostic benefits. Whether the extent of coronary artery disease interferes with these benefits has not been investigated yet.
aimsWe sought to compare the survival after percutaneous coronary intervention (PCI) for CTO between patients with multi- (MVD) and single-vessel disease (SVD).
methodsA total of 2002 consecutive patients undergoing CTO PCI between 01/2005 and 12/2013 were identified and stratified according to the presence/absence of MVD. The primary endpoint was all-cause mortality. Median follow-up was 2.6 (interquartile range 1.1-3.1) years.
resultsA total of 1634 (81.6%) patients had MVD. Procedural success rates were 81.5 and 89.7% in the MVD and SVD groups (p < 0.001). All-cause mortality during entire follow-up was higher in MVD as compared to SVD patients (13.5 versus 5.7%, p < 0.001), and differences were attenuated after multivariable adjustment for baseline characteristics [adjusted hazard ratio (HR) 1.51, 95% CI 0.98-2.33, p = 0.06]. The effect of successful CTO PCI on all-cause mortality was consistent among patients with MVD [11.0 versus 24.5%; adjusted HR 0.60, 95% CI 0.45-0.80, p < 0.001] and SVD [5.2 versus 10.5%; adjusted HR 0.74, 95% CI 0.24-2.26, p = 0.59, P
conclusionsSuccessful recanalization of a CTO is a strong independent predictor for reduced long-term mortality. Due a higher baseline risk, the absolute benefit in patients with MVD is substantially larger than in patients with SVD.
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