Evidence map›Paper›PMID 28235964›Full record

ArticleBMJ open2017

How does a physical activity programme in elementary school affect fracture risk? A prospective controlled intervention study in Malmo, Sweden.

Marcus E Cöster, Jesper Fritz, Jan-Åke Nilsson, Caroline Karlsson, Björn E Rosengren, Magnus Dencker, Magnus K Karlsson

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00633828 (Determinants for Peak Bone Mass, Skeletal Architecture, Fractures, Adipositas and Cardiovascular Risk Factors During Growth and Adulthood), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00633828 naactive not recruitingnot on this map

Determinants for Peak Bone Mass, Skeletal Architecture, Fractures, Adipositas and Cardiovascular Risk Factors During Growth and Adulthood

TypeinterventionalSponsorRegion SkaneRan1999 to 2050Enrolled500ConditionsFracturesArmsIncreased physical education in primary school (daily)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
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  11. Exercise and Peak Bone Mass.Current osteoporosis reports · 2020
    Review
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  14. Article
  15. Low physical activity is related to clustering of risk factors for fracture-a 2-year prospective study in children.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marcus E CösterDepartment of Orthopedics and Clinical Sciences, Clinical and Molecular Osteoporosis Research Unit, Malmö, Sweden.
Jesper FritzDepartment of Orthopedics and Clinical Sciences, Clinical and Molecular Osteoporosis Research Unit, Malmö, Sweden.
Jan-Åke NilssonDepartment of Orthopedics and Clinical Sciences, Clinical and Molecular Osteoporosis Research Unit, Malmö, Sweden.
Caroline KarlssonDepartment of Orthopedics and Clinical Sciences, Clinical and Molecular Osteoporosis Research Unit, Malmö, Sweden.
Björn E RosengrenDepartment of Orthopedics and Clinical Sciences, Clinical and Molecular Osteoporosis Research Unit, Malmö, Sweden.
Magnus DenckerDepartment of Physiology and Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden.
Magnus K KarlssonDepartment of Orthopedics and Clinical Sciences, Clinical and Molecular Osteoporosis Research Unit, Malmö, Sweden.
Lund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesRecent evidence from the 7-year follow-up of the Pediatric Osteoporosis Prevention (POP) study indicates an inverse correlation between years of participation in a physical activity (PA) intervention and fracture risk in children. However, we could not see a statistically significant reduction in fracture risk, which urged for an extension of the intervention.

settingThe study was conducted in 4 neighbouring elementary schools, where 1 school functioned as intervention school.

participantsWe included all children who began first grade in these 4 schools between 1998 and 2012. This resulted in 1339 children in the intervention group and 2195 children in the control group, all aged 6-8 years at the state of the study.

interventionWe launched an 8-year intervention programme with 40 min of moderate PA per school day, while the controls continued with the Swedish national standard of 60 min of PA per week. PRIMARY OUTCOME MEASURE: We used the regional radiographic archive to register objectively verified fractures and we estimated annual fracture incidences and incidence rate ratios (IRRs).

resultsDuring the first year after initiation of the intervention, the fracture IRR was 1.65 (1.05 to 2.08) (mean 95% CI). For each year of the study, the fracture incidence rate in the control group compared with the intervention group increased by 15.7% (5.6% to 26.8%) (mean 95% CI). After 8 years, the IRR of fractures was 52% lower in the intervention group than in the control group (IRR 0.48 (0.25 to 0.91) (mean 95% CI))].

conclusionsIntroduction of the school-based intervention programme is associated with a higher fracture risk in the intervention group during the first year followed by a gradual reduction, so that during the eighth year, the fracture risk was lower in the intervention group. TRIAL REGISTRATION NUMBER: NCT00633828.

Indexed as

ExerciseAdolescentCase-Control StudiesChildFemaleFractures, BoneHealth PromotionHumansIncidenceLongitudinal StudiesMaleOsteoporosisProspective StudiesRisk FactorsSchool Health ServicesSchoolsPUBLIC HEALTHSPORTS MEDICINE

Identifiers

PMID28235964
PMCPMC5337742
OpenAlexW2589876724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.